Structural characterization of a novel marine polysaccharide from mussel and its antioxidant activity in RAW264.7 cells induced by H2O2

文献类型： 外文期刊

第一作者： Xiang, Xing-Wei

作者： Xiang, Xing-Wei;Wang, Rui;Chen, Hui;Chen, Yu-Feng;Liu, Shu-Lai;Sun, Pei-Long;Xiang, Xing-Wei;Wang, Rui;Chen, Hui;Chen, Yu-Feng;Liu, Shu-Lai;Sun, Pei-Long;Xiang, Xing-Wei;Wang, Rui;Chen, Hui;Chen, Yu-Feng;Liu, Shu-Lai;Sun, Pei-Long;Shen, Guo-Xin;Chen, Lin

作者机构：

关键词： Mussel polysaccharide; Structural characterization; Antioxidant activity

期刊名称：FOOD BIOSCIENCE （ 影响因子：5.318； 五年影响因子：5.846 ）

ISSN： 2212-4292

年卷期： 2022 年 47 卷

页码：

收录情况： SCI

摘要： In this study, a new type of water-soluble polysaccharide was extracted and purified from mussels, and its structure and cellular antioxidant levels were studied. Mussel polysaccharide (MP 4.25 x 10(3) Da) is composed mainly of glucose, with a small amount of galactosamine hydrochloride, glucosamine hydrochloride, and galactose. MP shows characteristic polysaccharide bands in Fourier transform NMR and infrared spectroscopy. The main chain connection mode of MP is the glycosidic bond of -> 4)-alpha-D-Glcp-(1 -> , and the end group alpha-D-Glcp(1 -> and alpha-D-Glcp-(1 -> 6)-alpha-D-Glcp-(1 -> pass -> 4,6)-alpha-D-Glcp-(1 -> . The O-6 bond is connected to the main chain. Moreover, MP could protect RAW264.7 cells against H2O2-induced oxidative stress by increasing catalase (CAT), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) activities and reducing the content of malondialdehyde (MDA). This is expected to make MP an important member of the antioxidant family.

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