文献类型： 外文期刊
第一作者： Li, Jingying
作者： Li, Jingying;Zhang, Chen;He, Yubing;Li, Shaoya;Yan, Lei;Li, Yucai;Zhu, Ziwei;Xia, Lanqin;Li, Jingying;He, Yubing;Li, Shaoya;Xia, Lanqin
作者机构：
关键词： base editing; CRISPR; Cas; plants; precision genome editing; prime editing
期刊名称：JOURNAL OF INTEGRATIVE PLANT BIOLOGY （ 影响因子：11.4； 五年影响因子：10.1 ）
ISSN： 1672-9072
年卷期： 2023 年 65 卷 2 期
页码：
收录情况： SCI
摘要： Precise replacement of an allele with an elite allele controlling an important agronomic trait in a predefined manner by gene editing technologies is highly desirable in crop improvement. Base editing and prime editing are two newly developed precision gene editing systems which can introduce the substitution of a single base and install the desired short indels to the target loci in the absence of double-strand breaks and donor repair templates, respectively. Since their discoveries, various strategies have been attempted to optimize both base editor (BE) and prime editor (PE) in order to improve the precise editing efficacy, specificity, and expand the targeting scopes. Here, we summarize the latest development of various BEs and PEs, as well as their applications in plants. Based on these progresses, we recommend the appropriate BEs and PEs for both basic plant research and crop improvement. Moreover, we propose the perspectives for further optimization of these two editors. We envision that both BEs and PEs will become the routine and customized precise gene editing tools for both plant biological research and crop improvement in the near future.
分类号：
- 相关文献
作者其他论文 更多>>
-
Pristine/magnesium-loaded biochar and ZVI affect rice grain arsenic speciation and cadmium accumulation through different pathways in an alkaline paddy soil
作者：Zhang, Chen;Shi, Dong;Wang, Chao;Hu, Yanxia;Li, Xiaona;Hou, Yanhui;Zheng, Ruilun;Zhang, Chen;Li, Huafen;Sun, Guoxin
关键词：Cadmium (Cd); Arsenic (As) speciation; Co-contamination; Magnesium-loaded biochar; Zero-valent iron (ZVI); Rice
-
Imidacloprid triggered changes in strawberry fruits on edible quality and phenolic profiles by applied at two growth stages
作者：Yue, Ning;Zhang, Chen;Li, Simeng;Wang, Hongping;Li, Xiaohui;Chen, Xueying;Jin, Fen
关键词：Cyanidin-3-O-glucoside; Fruit-bearing completion; Fruit maturation; Imidacloprid application; Neonicotinoid insecticide; Strawberry quality
-
Genotypic and Phenotypic Characteristics of Lactic Acid Bacteria Associated with Forage Plants in the Native Grassland of Western Inner Mongolia and Their Application for Alfalfa Silage Fermentation
作者：Li, Wenlong;Li, Feng;Zhang, Chen;Gao, Jie;Tao, Ya;Tao, Ya;Tao, Ya
关键词：Inner Mongolia; natural forage plant; Lactiplantibacillus plantarum; Pediococcus pentosaceus; alfalfa silage
-
Application of organic manure as a potential strategy to alleviate the limitation of microbial resources in soybean rhizospheric and bulk soils
作者：Wu, Zhimin;Yan, Lei;Han, Xiaozeng;Chen, Xu;Lu, Xinchun;Yan, Jun;Zou, Wenxiu;Wang, Wei
关键词：enzymatic stoichiometry; rhizosphere; phospholipid fatty acids; soybean; organic manure
-
The Effect of Corner Structure on the Optimisation of Fishable Flow Field in Aquaculture Tanks
作者：Zhang, Fan;Cui, Mingchao;Liu, Huang;Zhang, Chen;Zhang, Fan;Zhang, Chen
关键词：aquaculture vessel; corner ratio; fishability; effluent effect; eddy strength
-
Soil organic matter components and sesquioxides integrally regulate aggregate stability and size distribution under erosion and deposition conditions in southern China
作者：Guo, Geng;Kong, Yu;Peng, Xiaoying;Ouyang, Zhen;Lin, Jie;Xu, Yanyin;Niu, Manting;Zeng, Guangruo;Liu, Jun;Zhang, Chen
关键词：Soil aggregate stability; Water erosion; Landscape positions; Soil organic matter fractions; Iron and aluminum oxides
-
Estimation of annual soil CO2 efflux under the erosion and deposition conditions by measuring and modeling its respiration rate in southern China
作者：Guo, Geng;Kuai, Jie;Peng, Xiaoying;Lin, Jie;Li, Xiao;Zhang, Xiang;Xu, Yanyin;Zeng, Guangruo;Liu, Jun;Zhang, Chen;Lin, Jie
关键词：Soil carbon efflux; Soil temperature; Soil moisture; Water erosion; Red soil
