文献类型： 外文期刊
第一作者： Zhang, Cheng
作者： Zhang, Cheng;Cui, Huan;Li, Entao;Guo, Zhendong;Wang, Tiecheng;Yan, Fang;Liu, Lina;Li, Yuanguo;Chen, Di;Meng, Keyin;Li, Nan;Gao, Yuwei;Zhang, Chunmao;Zhang, Cheng;Liu, Juxiang;Cui, Huan;Qin, Chengfeng
作者机构：
关键词： SARS-CoV-2; B; 1; 351; contact transmission; mice; rats
期刊名称：FRONTIERS IN IMMUNOLOGY （ 影响因子：8.786； 五年影响因子：8.876 ）
ISSN： 1664-3224
年卷期： 2022 年 13 卷
页码：
收录情况： SCI
摘要： Previous studies have shown that B.1.351 and other variants have extended the host range of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to mice. Sustained transmission is a prerequisite for viral maintenance in a population. However, no evidence of natural transmission of SARS-CoV-2 in wild mice has been documented to date. Here, we evaluated the replication and contact transmission of the B.1.351 variant in mice and rats. The B.1.351 variant could infect and replicate efficiently in the airways of mice and rats. Furthermore, the B.1.351 variant could not be transmitted in BALB/c or C57BL/6 mice but could be transmitted with moderate efficiency in rats by direct contact. Additionally, the B.1.351 variant did not transmit from inoculated Syrian hamsters to BALB/c mice. Moreover, the mouse-adapted SARS-CoV-2 strain C57MA14 did not transmit in mice. In summary, the risk of B.1.351 variant transmission in mice is extremely low, but the transmission risk in rats should not be neglected. We should pay more attention to the potential natural transmission of SARS-CoV-2 variants in rats and their possible spillback to humans.
分类号：
- 相关文献
作者其他论文 更多>>
-
Accelerating biological imaging of atomic force microscopy by deep-learning
作者：Yu, Haiyue;Wang, Baichuan;Song, Hangze;Wang, Zuobin;Wang, Zuobin;Wang, Zuobin;Li, Nan;Wang, Zuobin;Wang, Zuobin;Yao, Feifan
关键词：Atomic force microscopy; Deep-learning; Virus; Particles characterization; Super-resolution reconstruction
-
Effervescence-assisted salting-out liquid-liquid extraction for rapid and convenient analysis of pyrethroid pesticide residues
作者：Li, Wenxuan;Wang, Meifei;Wang, Yuyang;Chen, Di;Xu, Yaxi;Wei, Jinchao
关键词：Salting-out assisted liquid-liquid extraction; Effervescence; Pyrethroid insecticides; Gas chromatography with an electron capture; detector; Juices; Herbal extract
-
Emerging West African Genotype Chikungunya Virus in Mosquito Virome
作者：Xiao, Pengpeng;Hao, Yujia;Yuan, Yuge;Ma, Wenzhou;Li, Nan;Li, Yiquan;Zhang, He
关键词：Virome; mosquito; Chikungunya virus; phylogenetic analysis; virus variation
-
Insight into the enhancement and mechanism of saltiness perception by salty peptides from bovine bone
作者：Wang, Haiyan;Lu, Wenjing;Chen, Di;Chen, Xuan;Zhang, Cen;Xiao, Chaogeng;Wang, Haiyan;Xiao, Chaogeng;Dang, Yali;Chen, Xuan;Gou, Zhongjun;Wang, Yongjun
关键词：Salty peptides; TMC4; Sodium reduction; Stevens' law; Molecular dynamics simulation
-
Dynamics of antibiotic resistance in poultry farms via multivector analysis
作者：Shen, Dan;Li, Chunmei;Guo, Zhendong
关键词：Metagenomics; Antibiotics resistance gene; Poultry farm; Multivector
-
Effect of heat exposure on proliferation-promoting activity, growth-factor-like components and metabolism profile of newly secreted royal jelly
作者：Chen, Di;Lu, Wenjing;Zhang, Cen;Xiao, Chaogeng;Wang, Huimin David;Guo, Huiyuan;Lin, Ligen
关键词：Bee product; Heat; Functional food; Storage; Quality
-
Effects of the trehalose and star anise extract on the water retention of pork meatballs and the functional structure of myofibrillar protein
作者：Li, Nan;Zhang, Muhan;Li, Pengpeng;Sun, Chong;Xu, Weimin;Li, Jiaolong;Wang, Daoying;Li, Nan;Zhang, Muhan;Li, Pengpeng;Sun, Chong;Xu, Weimin;Li, Jiaolong;Wang, Daoying;Li, Nan;Zhang, Muhan;Li, Pengpeng;Sun, Chong;Xu, Weimin;Li, Jiaolong;Wang, Daoying
关键词：trehalose; star anise extract; pork meatball; water-holding capacity; antioxidant capacity; myofibrillar protein
