A 14-bp deletion in bovine EPAS1 gene is associated with carcass traits

文献类型： 外文期刊

第一作者： Jiang, Enhui

作者： Jiang, Enhui;Wang, Hongyang;Li, Xuelan;Bi, Yi;Mao, Cui;Lan, Xianyong;Jiang, Fugui;Song, Enliang;Lan, Xianyong;Song, Enliang

作者机构：

关键词： EPAS1; cattle; carcass traits; polymorphism; association

期刊名称：ANIMAL BIOTECHNOLOGY （ 影响因子：3.7； 五年影响因子：3.3 ）

ISSN： 1049-5398

年卷期： 2023 年

页码：

收录情况： SCI

摘要： EPAS1 (Endothelial PAS Domain Protein 1) gene is well-known for its function in plateau hypoxia adaptability. It encodes HIF-2 alpha, which involved in the induction of genes regulated by oxygen and then affects multiple physiological processes such as angiogenesis and energy metabolism. All of these indicate it may affect the development of animals. In this study, a 14-bp deletion in EPAS1 gene was uncovered in Shandong black cattle population (n = 502). Two genotypes (II and ID) were found and the frequency of the homozygous II genotype is higher than the heterozygous ID genotype. This population is consisted with HWE (p > 0.05). And more importantly, the 14-bp deletion was associated with outside flat (p = 0.003), brisket (p = 0.001), and knuckle (p = 0.032). These findings suggested that the 14-bp deletion is significantly associated with carcass traits, which could be served as a molecular marker applied to cow breeding.

分类号：

  • 相关文献
作者其他论文 更多>>
  • Muscle Characteristics Comparison Analysis Reveal Differences in the Meat Quality and Nutritional Components of Three Shanghai Local Pig Breeds

    作者：Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong;Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong;Jiang, Wei;He, Chuan;Bai, Lan;Wu, Xiao

    关键词：local pig breeds; meat quality traits; amino acids; texture; flavored nucleotide

  • Investigation of the Molecular Mechanism of Asthma in Meishan Pigs Using Multi-Omics Analysis

    作者：Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong;Li, Xin;Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong;Tu, Weilong;Wang, Hongyang;Zhang, Yingying;Huang, Ji;Diao, Yuduan;Zhou, Jieke;Tan, Yongsong

    关键词：Meishan pig; asthma; transcriptome; metabolome

  • Flavor characterization of pork cuts in Chalu black pigs using multi-omics analysis

    作者：Zhang, Yingying;Diao, Yuduan;Huang, Ji;Wang, Hongyang;Tu, Weilong;Zhang, Jiajie;Zhou, Jieke;Tan, Yongsong;Zhang, Yingying;Diao, Yuduan;Huang, Ji;Wang, Hongyang;Tu, Weilong;Zhou, Jieke;Tan, Yongsong;Raza, Sayed Haidar Abbas;Zhang, Jiajie

    关键词：Pork; Meat flavor; Muscle fiber type; Chinese indigenous pig; Multi-omics; Chalu black pigs

  • The Multifaceted Impact of Karrikin Signaling in Plants

    作者：Deng, Qilin;Wang, Hongyang;Qiu, Yanhong;Wang, Dexin;Xia, Yang;Zhang, Yumeng;Pei, Manying;Zhao, Yinling;Xu, Xiulan;Zhang, Haijun;Deng, Qilin;Zhang, Yumeng;Pei, Manying;Zhao, Yinling;Wang, Hongyang;Qiu, Yanhong;Wang, Dexin;Xia, Yang;Xu, Xiulan;Zhang, Haijun

    关键词：biological function; karrikins (KARs); KARRIKIN INSENSITIVE2 (KAI2); plant growth; stress tolerance; signal transduction

  • Genome-Wide Association Study That Identifies Molecular Markers with Freezing Resistance in Duroc Boar Sperm

    作者：Zhang, Jiajun;Li, Meicheng;Tao, Chenyu;Wang, Wenjun;Chen, Guangxiang;Li, Bushe;Zhang, Hejun;Wang, Hongyang

    关键词：Duroc; GWAS; boar sperm freezability; biomarker; candidate gene

  • Occurrence of Co-Contamination and Interaction of Multi-Mycotoxins in Dairy Cow Feed in China

    作者：Zhu, Zuoyin;Cheng, Haisheng;Wang, Jie;Zhou, Xinli;Zhu, Zuoyin;Cheng, Haisheng;Wang, Jie;Wang, Jianhua;Yang, Junhua;Ma, Junmei;Wang, Hongyang

    关键词：feed; mycotoxin; co-contamination; correlation; interaction

  • EasyMetagenome: A user-friendly and flexible pipeline for shotgun metagenomic analysis in microbiome research

    作者：Bai, Defeng;Xun, Jiani;Ma, Chuang;Luo, Hao;Yang, Haifei;Hou, Huiyu;Lv, Hujie;Wan, Xiulin;Wang, Yao;Yousuf, Salsabeel;Zeng, Meiyin;Zhang, Tianyuan;Gao, Yunyun;Liu, Yong-Xin;Chen, Tong;Ma, Chuang;Yang, Haifei;Cao, Chen;Cao, Xiaofeng;Cui, Jianzhou;Deng, Yuan-Ping;Deng, Zhaochao;Yu, Hao;Zhang, Chunfang;Dong, Wenxin;Dong, Wenxue;Du, Juan;Fang, Qunkai;Fang, Wei;Fang, Yue;Luan, Yaning;Fu, Fangtian;Fu, Min;Fu, Yi-Tian;Gao, He;Ge, Jingping;Guo, Yuhao;Gong, Qinglong;Lou, Wenbo;Gu, Lunda;Yang, Li;Guo, Peng;Hai, Tang;Liu, Hao;He, Jieqiang;He, Zi-Yang;Huang, Can;Ji, Shuai;Jiang, ChangHai;Jiang, Gui-Lai;Jiang, Lingjuan;Jin, Ling N.;Li, Changchao;Kan, Yuhe;Kang, Da;Kou, Jin;Lam, Ka-Lung;Li, Chong;Li, Fuyi;Li, Liwei;Li, Miao;Li, Xin;Li, Ye;Li, Zheng-Tao;Zhu, Chengshuai;Liang, Jing;Mo, Jiayuan;Lin, Yongxin;Liu, Changzhen;Liu, Danni;Zhang, Jing;Chen, Shifu;Liu, Fengqin;Liu, Jia;Liu, Tianrui;Liu, Tingting;Wang, Xinlong;Liu, Xinyuan;Luo, Yuanyuan;Liu, Yaqun;Liu, Bangyan;Liu, Minghao;Lv, Hujie;Ma, Tengfei;Mai, Zongjiong;Niu, Dongze;Pan, Zhuo;Qi, Heyuan;Shi, Zhanyao;Song, Chunjiao;Sun, Fuxiang;Sun, Yan;Tian, Sihui;Wang, Guoliang;Wang, Hongyang;Wang, Hongyu;Wang, Huanhuan;Wang, Jing;Wang, Jun;Wang, Kang;Wang, Leli;Yao, Xiaofang;Wang, Shao-kun;Xiao, Zufei;Xing, Huichun;Xu, Yifan;Yang, Song;Yan, Shu-yan;Zhang, Yi-Bo;Yang, Yuanming;Lei, Yu;Yuan, Zhengrong;Zhang, Chunge;Zhang, Huimin;Zhang, Na;Zhang, Yupeng;Zhang, Zheng;Zhou, Mingda;Zhou, Yuanping;Zhu, Zhihao;Zhu, Lin;Zhu, Yue;Zou, Hongqin;Zuo, Anna;Dong, Wenxuan;Wen, Tao;Chen, Shifu;Chen, Shifu;Li, Guoliang

    关键词：metagenome; microbiome; microbiota; pipeline; visualization

微信小程序