Acoustofluidic precise manipulation: Recent advances in applications for micro/nano bioparticles

文献类型： 外文期刊

第一作者： Li, Wanglu

作者： Li, Wanglu;Ye, Zihong;Li, Wanglu;Yao, Zhihao;He, Kaiyu;Wang, Liu;Wang, Hongmei;Xu, Xiahong;Li, Wanglu;Ma, Tongtong;Fu, Yingchun;Xu, Xiahong;Yao, Zhihao

作者机构：

关键词： Bioparticles; Bulk acoustic wave; Surface acoustic wave; Acoustic tweezers; Acoustofluidic chips

期刊名称：ADVANCES IN COLLOID AND INTERFACE SCIENCE （ 影响因子：15.9； 五年影响因子：16.4 ）

ISSN： 0001-8686

年卷期： 2024 年 332 卷

页码：

收录情况： SCI

摘要： Acoustofluidic technologies that integrate acoustic waves and microfluidic chips have been widely used in bioparticle manipulation. As a representative technology, acoustic tweezers have attracted significant attention due to their simple manufacturing, contact-free operation, and low energy consumption. Recently, acoustic tweezers have enabled the efficient and smart manipulation of biotargets with sizes covering millimeters (such as zebrafish) and nanometers (such as DNA). In addition to acoustic tweezers, other related acoustofluidic chips including acoustic separating, mixing, enriching, and transporting chips, have also emerged to be powerful platforms to manipulate micro/nano bioparticles (cells in blood, extracellular vesicles, liposomes, and so on). Accordingly, some interesting applications were also developed, such as smart sensing. In this review, we firstly introduce the principles of acoustic tweezers and various related technologies. Second, we compare and summarize recent applications of acoustofluidics in bioparticle manipulation and sensing. Finally, we outlook the future development direction from the perspectives such as device design and interdisciplinary.

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