Optimizing the Ultrasound-Assisted Extraction of Total Cardiac Glycosides from the Milk of Calotropis Gigantea with Response Surface Methodology

文献类型: 外文期刊

第一作者: Gao, Z. Y.

作者: Gao, Z. Y.;Gong, R.;Zha, F.;Gong, R.;Gao, F.

作者机构:

关键词: ultrasound-assisted extraction; cardiac glycoside; Calotropis gigantea; response surface method; Box-Behnken design

期刊名称:THEORETICAL FOUNDATIONS OF CHEMICAL ENGINEERING ( 影响因子:0.8; 五年影响因子:0.7 )

ISSN: 0040-5795

年卷期: 2023 年 57 卷 SUPPL 1 期

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收录情况: SCI

摘要: The ultrasound-assisted extraction was carried out to separate the total cardiac glycoside from the milk of Calotropis gigantea, and the extraction factors was optimized by response surface method using the Box-Behnken design (BBD) on total cardiac glycoside extraction was determined and optimized. A quadratic polynomial parameter mathematical model was established. Under the optimized conditions of ethanol concentration = 40% (vol), liquid-material ratio = 40 : 1, ultrasound power = 420 W and ultrasonic time = 30 min, the total cardiac glycoside yield is 12.75%, which is very close to the predicted value of 12.48%. The model predicts the experimental data well and has a high determination coefficient (R-2 = 0.992). The variables that have a greater influence on the extraction yield were selected as ultrasonic power, ultrasonic time, ethanol concentration and liquid-material ratio, respectively.

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