Bioactive Peptides Derived from Tuna: Screening, Extraction, Bioactivity, and Mechanism of Action

文献类型: 外文期刊

第一作者: Cheng, Jing-an

作者: Cheng, Jing-an;Wang, Di;Yu, Gang;Chen, Shengjun;Ma, Zhenhua;Wei, Ya;Zhao, Xue;Li, Chunsheng;Wang, Yueqi;Zhao, Yongqiang;Cheng, Jing-an;Wang, Di;Yu, Gang;Chen, Shengjun;Ma, Zhenhua;Wei, Ya;Zhao, Xue;Li, Chunsheng;Wang, Yueqi;Zhao, Yongqiang;Zhang, Yi;Cao, Rong

作者机构:

关键词: tuna; bioactive peptides; antioxidant; antihypertensive; human health

期刊名称:MARINE DRUGS ( 影响因子:5.4; 五年影响因子:5.6 )

ISSN:

年卷期: 2025 年 23 卷 7 期

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收录情况: SCI

摘要: Peptides play a crucial role in the development of pharmaceuticals and functional foods. Multiple studies have shown that natural bioactive peptides possess antioxidant, antihypertensive, anti-tumor, and anti-inflammatory activities. Marine bioactive peptides, especially those sourced from fish, constitute a substantial reservoir of these molecules. Although considerable research has been undertaken on fish-derived peptides, studies specifically concerning those from tuna are limited. Tuna, a marine fish of high nutritional value, generates substantial by-product waste during fishing and processing. Therefore, it is essential to conduct an evaluation of the advancements in study on tuna-derived active peptides and to offer a perspective on the direction of future investigations. This review integrates prospective bioactive peptides derived from tuna and reports contemporary strategies for their investigation, including extraction, purification, screening, identification, and activity evaluation procedures, including Yeast Surface Display (YSD) and molecular docking. This review seeks to promote the continued investigation and application of bioactive peptides derived from tuna.

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