Molecular analysis based on the amino acid sequence of acetylcholinesterase from Myzus persicae (Hemiptera: Aphididae)

文献类型: 外文期刊

第一作者: Zhou, Benguo

作者: Zhou, Benguo;Lei, Yanli;Xu, Dafeng;Gao, Zhengliang;Tang, Qingfeng;Jiang, Junqi

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关键词: acetylcholinesterase: AChE;9000-81-1;EC 3.1.1.7;phylogenetic relationship;amino add sequence

期刊名称:JOURNAL OF FOOD AGRICULTURE & ENVIRONMENT ( 影响因子:0.435; 五年影响因子:0.484 )

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收录情况: SCI

摘要: Acetylcholinesterase (AChE) is a key enzyme of the insect nerve system. The enzyme is the primary target of organophosphorous and carbamate insecticides. In this study, we compared the amino acid sequences of AChEs from the organisms tested and found that amino acid sequence of AChEs showed the biggest evolution and conservation. The amino acid sequence of AChEs from Myzus persicae was obtained and analyzed. Phylogenetic tree was created based on the amino acid sequence of AChEs in which the phylogenetic relationship of the organisms tested can be exhibited. Homology modeling was completed and the AChEs structure and key amino acid points from the aphids tested was viewed. This paper also discussed the M persicae AChEs structure characteristics and functional sites.

分类号: TS2

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