Royal Jelly: Beneficial Properties and Synergistic Effects with Chemotherapeutic Drugs with Particular Emphasis in Anticancer Strategies

文献类型： 外文期刊

第一作者： Salama, Suzy

作者： Salama, Suzy;Shou, Qiyang;Abd El-Wahed, Aida A.;Elias, Nizar;Xiao, Jianbo;Swillam, Ahmed;Umair, Muhammad;Guo, Zhiming;Daglia, Maria;Daglia, Maria;El-Seedi, Hesham R.;Wang, Kai;Khalifa, Shaden A. M.;El-Seedi, Hesham R.;El-Seedi, Hesham R.;El-Seedi, Hesham R.

作者机构：

关键词： royal jelly; cancer; anticancer drugs; synergistic effect

期刊名称：NUTRIENTS （ 影响因子：6.706； 五年影响因子：7.185 ）

ISSN：

年卷期： 2022 年 14 卷 19 期

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收录情况： SCI

摘要： Cancer is one of the major causes of death globally. Currently, various methods are used to treat cancer, including radiotherapy, surgery, and chemotherapy, all of which have serious adverse effects. A healthy lifestyle, especially a nutritional diet, plays a critical role in the treatment and prevention of many disorders, including cancer. The above notion, plus the trend in going back to nature, encourages consumers and the food industry to invest more in food products and to find potential candidates that can maintain human health. One of these agents, and a very notable food agent, is royal jelly (RJ), known to be produced by the hypopharyngeal and mandibular salivary glands of young nurse honeybees. RJ contains bioactive substances, such as carbohydrates, protein, lipids, peptides, mineral salts and polyphenols which contribute to the appreciated biological and pharmacological activities. Antioxidant, anticancer, anti-inflammatory, antidiabetic, and antibacterial impacts are among the well-recognized benefits. The combination of RJ or its constituents with anticancer drugs has synergistic effects on cancer disorders, enhancing the drug's effectiveness or reducing its side effects. The purpose of the present review is to emphasize the possible interactions between chemotherapy and RJ, or its components, in treating cancer illnesses.

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