Advancements in the Application of scRNA-Seq in Breast Research: A Review

文献类型： 外文期刊

第一作者： Zhang, Zhenyu

作者： Zhang, Zhenyu;Liang, Chunnian;Zhang, Zhenyu;Ma, Xiaoming;La, Yongfu;Guo, Xian;Chu, Min;Bao, Pengjia;Yan, Ping;Wu, Xiaoyun;Liang, Chunnian;Zhang, Zhenyu;Ma, Xiaoming;La, Yongfu;Guo, Xian;Chu, Min;Bao, Pengjia;Yan, Ping;Wu, Xiaoyun;Liang, Chunnian

作者机构：

关键词： scRNA-seq; breast; single cell; advancements

期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：4.9； 五年影响因子：5.7 ）

ISSN： 1661-6596

年卷期： 2024 年 25 卷 24 期

页码：

收录情况： SCI

摘要： Single-cell sequencing technology provides apparent advantages in cell population heterogeneity, allowing individuals to better comprehend tissues and organs. Sequencing technology is currently moving beyond the standard transcriptome to the single-cell level, which is likely to bring new insights into the function of breast cells. In this study, we examine the primary cell types involved in breast development, as well as achievements in the study of scRNA-seq in the microenvironment, stressing the finding of novel cell subsets using single-cell approaches and analyzing the problems and solutions to scRNA-seq. Furthermore, we are excited about the field's promising future.

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