Interfacially Self-Assembled Mutifunctional Protein Thin Films for Accelerated Wound Healing

文献类型： 外文期刊

第一作者： Geng, Yajiao

作者： Geng, Yajiao;Gao, Yuze;Guo, Jialiang;Hao, Hao;Hao, Fengjie;Luo, Quan;Hu, Juntao;Li, Tiezhu;Chen, Yihao;Huang, Wei;Luo, Quan

作者机构：

期刊名称：ACS MACRO LETTERS （ 影响因子：5.1； 五年影响因子：5.7 ）

ISSN：

年卷期： 2024 年

页码：

收录情况： SCI

摘要： The design of mutifunctional protein films for large-area spatially ordered arrays of functional components holds great promise in the field of biomedical applications. Herein, interfacial electrostatic self-assembly was employed to construct a large-scale protein thin film by inducing electrostatic interactions between three bovine serum albumin (BSA)-coated nanoclusters and cetyltrimethylammonium bromide (CTAB), leading to their spontaneous organization and uniform distribution at the oil-water interface. This protein film demonstrated excellent multienzyme functions, high antibacterial activity, and pH-responsive drug release capability. Therefore, it can accelerate the wound closure process through a synergistic effect that includes reducing local blood glucose levels, regulating cellular oxidative stress, eradicating bacteria, and promoting cell proliferation.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序