The haplotype-resolved T2T reference genome highlights structural variation underlying agronomic traits of melon

文献类型: 外文期刊

第一作者: Li, Guoli

作者: Li, Guoli;Tang, Lingli;He, Yuhua;Xu, Yongyang;Zhao, Guangwei;Li, Guoli;Lin, Tao;Tang, Lingli;He, Yuhua;Xu, Yongyang;Zhao, Guangwei;Tang, Lingli;Zhao, Guangwei;Bendahmane, Abdelhafid;Garcia-Mas, Jordi;Garcia-Mas, Jordi

作者机构:

期刊名称:HORTICULTURE RESEARCH ( 影响因子:8.7; 五年影响因子:9.0 )

ISSN: 2662-6810

年卷期: 2023 年 10 卷 10 期

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收录情况: SCI

摘要: Melon (Cucumis melo L.) is an important vegetable crop that has an extensive history of cultivation. However, the genome of wild and semi-wild melon types that can be used for the analysis of agronomic traits is not yet available. Here we report a chromosome-level T2T genome assembly for 821 (C. melo ssp. agrestis var. acidulus), a semi-wild melon with two haplotypes of similar to 373 Mb and similar to 364 Mb, respectively. Comparative genome analysis discovered a significant number of structural variants (SVs) between melo (C. melo ssp. melo) and agrestis (C. melo ssp. agrestis) genomes, including a copy number variation located in the ToLCNDV resistance locus on chromosome 11. Genome-wide association studies detected a significant signal associated with climacteric ripening and identified one candidate gene CM_ac12g14720.1 (CmABA2), encoding a cytoplasmic short chain dehydrogenase/reductase, which controls the biosynthesis of abscisic acid. This study provides valuable genetic resources for future research on melon breeding.

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