When cyclin-dependent kinases meet viral infections, including SARS-CoV-2

文献类型: 外文期刊

第一作者: Yan, Yan

作者: Yan, Yan;Tang, Yan-Dong;Zheng, Chunfu;Tang, Yan-Dong;Zheng, Chunfu

作者机构:

关键词: CDKs; DNA viruses; RNA viruses; viral infection

期刊名称:JOURNAL OF MEDICAL VIROLOGY ( 影响因子:20.693; 五年影响因子:12.203 )

ISSN: 0146-6615

年卷期: 2022 年 94 卷 7 期

页码:

收录情况: SCI

摘要: Cyclin-dependent kinases (CDKs) are protein kinases that play a key role in cell division and transcriptional regulation. Recent studies have demonstrated the critical roles of CDKs in various viral infections. However, the molecular processes underpinning CDKs' roles in viral infection and host antiviral defense are unknown. This minireview briefly overviews CDKs' functions and highlights the most recent discoveries of CDKs' emerging roles during viral infections, thereby providing a scientific and theoretical foundation for antiviral regulation and shedding light on developing novel drug targets and therapeutic strategies against viral infection.

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