Brucellae as resilient intracellular pathogens: epidemiology, host-pathogen interaction, recent genomics and proteomics approaches, and future perspectives

文献类型： 外文期刊

第一作者： Dawood, Ali Sobhy

作者： Dawood, Ali Sobhy;Algharib, Samah Attia;Luo, Wanhe;Dawood, Ali Sobhy;Guo, Aizhen;Dawood, Ali Sobhy;Elrashedy, Alyaa;Nayel, Mohamed;Salama, Akram;Zaghawa, Ahmed;Elsify, Ahmed;Mousa, Walid;Zhao, Gang;Algharib, Samah Attia;Algharib, Samah Attia;Algharib, Samah Attia;Zubair, Muhammed

作者机构：

关键词： emerging Brucella pathogens; contagious disease; prevention and control; Brucella vaccines; genomics and proteomics approaches; future perspectives

期刊名称：FRONTIERS IN VETERINARY SCIENCE （ 影响因子：3.2； 五年影响因子：3.5 ）

ISSN：

年卷期： 2023 年 10 卷

页码：

收录情况： SCI

摘要： Brucellosis is considered one of the most hazardous zoonotic diseases all over the world. It causes formidable economic losses in developed and developing countries. Despite the significant attempts to get rid of Brucella pathogens in many parts of the world, the disease continues to spread widely. Recently, many attempts proved to be effective for the prevention and control of highly contagious bovine brucellosis, which could be followed by others to achieve a prosperous future without rampant Brucella pathogens. In this study, the updated view for worldwide Brucella distribution, possible predisposing factors for emerging Brucella pathogens, immune response and different types of Brucella vaccines, genomics and proteomics approaches incorporated recently in the field of brucellosis, and future perspectives for prevention and control of bovine brucellosis have been discussed comprehensively. So, the current study will be used as a guide for researchers in planning their future work, which will pave the way for a new world without these highly contagious pathogens that have been infecting and threatening the health of humans and terrestrial animals.

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