A Major Facilitator Superfamily Transporter Is Critical for the Metabolism and Biogenesis of the Apicoplast
文献类型： 外文期刊
第一作者： Liang, Yumeng
作者： Liang, Yumeng;Qi, Wei;Fu, Jiawen;Jia, Honglin;Jia, Honglin
作者机构：
关键词：
期刊名称：PATHOGENS （ 影响因子：3.3； 五年影响因子：3.6 ）
ISSN：
年卷期： 2025 年 14 卷 8 期
页码：
收录情况： SCI
摘要： The apicoplast is a highly specialized organelle in the biosynthesis of essential metabolites in most of the apicomplexan protozoa. This organelle is surrounded by four layers of membranes. However, the molecular mechanisms mediating transmembrane transport are not yet fully understood. In this study, we conducted a phenotypic analysis to investigate the role of a major facilitator superfamily transporter (TgApMFS1) in the survival of the parasite. The results indicated that TgApMFS1 is critical for the survival of Toxoplasma gondii in cell culture conditions. Further analysis indicated that these transporters are crucial for the biogenesis of organelles and the metabolic processes of parasite.
分类号：
- 相关文献
作者其他论文 更多>>
-
A novel replication-deficient FCV vaccine provides strong immune protection in cats
作者：Heng, Wuchang;Zang, Dan;Li, Ruiyu;Jiang, Qian;Liu, Jiasen;Jia, Honglin;Kang, Hongtao;Jia, Honglin
关键词：replication-deficient FCV; vaccine; calicivirus
-
A colloidal gold immunochromatographic test strip based on mAbs anti-N protein to detect feline coronavirus
作者：Liu, Zhe;Yang, Yupeng;Qi, Ruibin;Gu, Haorong;Feng, Kexin;Jiang, Qian;Jia, Honglin;Kang, Hongtao;Liu, Jiasen;Chen, Mengru
关键词：feline coronavirus (FCoV); monoclonal antibody; identification of antigenic epitopes; colloidal gold immunochromatographic text strip
-
The effects of a combination of maize/peanut intercropping and residue return on soil microbial nutrient limitation in maize fields
作者：Yao, Fanyun;Cao, Yujun;Liang, Jie;Liu, Xiaodan;Liu, Zhiming;Lv, Yanjie;Wei, Wenwen;Xu, Wenhua;Wang, Yongjun;Qi, Wei;Wang, Yongjun;Yu, Yang;Li, Xiang;Feng, Jian
关键词：Soil nutrients; Microbial biomass; Extracellular enzymes; C:N:P stoichiometry; Nutrient limitation
-
Dynamic Immune Response Landscapes of Avian Peripheral Blood Post-Vaccination Against Infectious Bronchitis Virus Infection
作者：Li, Xuefeng;Liang, Yumeng;Zhang, Yu;Liu, Zheyi;Cui, Lu;Liu, Shengwang;Li, Hai;Li, Xuefeng;Liu, Zheyi;Cui, Lu;Xi, Miaomiao;Feng, Shufeng;Liu, Xiaoxiao;Zhu, Yongxin;Li, Hai
关键词：avian infectious bronchitis virus; adaptive immune responses; vaccine; immune landscape
-
Establishment of one-step duplex TaqMan real-time PCR for detection of feline coronavirus and panleukopenia virus
作者：Liu, Zhe;Jiang, Qian;Yang, Yupeng;Qi, Ruibin;Gu, Haorong;Feng, Kexin;Jia, Honglin;Kang, Hongtao;Liu, Jiasen;Chen, Mengru
关键词：Duplex TaqMan qPCR; FCoV; FPLV; Clinical detection
-
Single cell transcriptomics correlate avian coronavirus prime vaccination efficacy with antigen-presenting cell preference
作者：Li, Xuefeng;Fa, Botao;Liu, Zheyi;Cui, Lu;Xi, Miaomiao;Feng, Shufeng;Liu, Xiaoxiao;Xiao, Zhengtao;Li, Hai;Li, Xuefeng;Liang, Yumeng;Zhang, Yu;Liu, Zheyi;Cui, Lu;Xu, Li;Liu, Shengwang;Li, Hai
关键词：
-
A novel YGGT family protein is localized in the apicoplast and is essential for the organelle inheritance
作者：Su, Wenqiang;Gu, Haorong;Zheng, Jun;Jia, Honglin
关键词：
Toxoplasma gondii ; apicoplast; biogenesis; YGGT family protein;Tg YCAP
