Protective efficacy of commercial Newcastle disease vaccines against challenge of goose origin virulent Newcastle disease virus in geese

文献类型: 外文期刊

第一作者: Dai, Yabin

作者: Dai, Yabin;Liu, Mei;Li, Wenliang

作者机构:

关键词: Animals;Antibodies;Viral blood;China;Geese;Immunization veterinary;Newcastle Disease prevention & control;Newcastle disease virus immunology pathogenicity;Time Factors;Viral Vaccines immunology;Virulence

期刊名称:AVIAN DISEASES ( 影响因子:1.577; 五年影响因子:1.915 )

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收录情况: SCI

摘要: Since 1997, severe outbreaks of Newcastle disease (ND) in geese in many regions throughout China have resulted in high morbidity and mortality, and great economic loss to farmers; however, no licensed, specific vaccine is yet available for this disease in China. In this study, goslings were immunized with different combinations and dosages of several commercial ND vaccines including La Sota vaccine, Mukteswar vaccine, recombinant live vaccine against avian influenza (AI) and ND (rL-H5 strain), and inactivated ND oil-emulsion vaccine (La Sota strain). The protective effects were evaluated based upon the level of antibody response and the degree of protection against the goose-origin virulent NDV strain. The result showed that two doses (i.e., one more than that for chicken) of La Sota vaccine priming, followed by 2-5 doses of Mukteswar vaccine boosting 2-3 weeks later, not only induced higher HI antibody levels, but also conferred longer-lasting protection. This immunization procedure can be recommended for prevention of ND in geese.

分类号: S85

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