In vitro digestive properties and the bioactive effect of walnut green husk on human gut microbiota

文献类型： 外文期刊

第一作者： Zhao, Xiaolan

作者： Zhao, Xiaolan;Ying, Jiabao;Wang, Yulu;Li, Zhen;Gu, Tianyi;Liu, Shujun;Li, Yulong;Xin, Fengjiao;Wen, Boting;Zhao, Xiaolan;Liu, Bing;Wang, Zhuochen;Xin, Fengjiao;Wen, Boting

作者机构：

关键词： walnut green husk; in vitro digestion; in vitro fermentation; gut microbiota; metabolism

期刊名称：FRONTIERS IN MICROBIOLOGY （ 影响因子：4.5； 五年影响因子：5.2 ）

ISSN：

年卷期： 2024 年 15 卷

页码：

收录情况： SCI

摘要： Introduction Walnut green husk (WGH) is a waste byproduct from walnut industry. However, it is not well-known about its bioactive effect on human gut health. Methods This study conducted in vitro digestion and fermentation experiments to study the bioactive effect of WGH. Results Microbial fermentation was the primary mechanism to efficiently release phenolics and flavonoids, resulting in more excellent antioxidant capacities (DPPH, ABTS, and FRAP assays), which reached a highest value with 14.82 +/- 0.01 mg VcE/g DW, 3.47 +/- 0.01 mmol TE/g DW, and 0.96 +/- 0.07 mmol FeSO47H(2)O/g DW, respectively. The surface microstructure of WGH became loose and fragmented after microbial fermentation. The analytical results of gut microbiota demonstrated that WGH could significantly increase the relative abundance of Proteobacteria in phylum level and Phascolarctobacterium in genus level while certain pro-inflammatory bacteria (such as Clostridium_sensu_stricto_1, Dorea, Alistipes, and Bilophila) was inhibited. Additionally, 1,373 differential metabolites were identified and enriched in 283 KEGG pathways. Of which some metabolites were significantly upregulated including ferulic acid, chlorogenic acid, umbelliferone, scopolin, muricholic acid, and so forth. Discussion These results indicated that WGH could have antioxidant and anti-inflammatory activities in the human gut, which could improve the economical value of WGH in the food industry.

分类号：

  • 相关文献
作者其他论文 更多>>
  • Context-dependent response of crop pests to landscape composition

    作者：Yang, Long;Pan, Yunfei;Wyckhuys, Kris A. G.;Li, Minlong;Wang, Kaitao;Liu, Bing;Liu, Yangtian;Jia, Shuangshuang;Li, Qian;Li, Yan;Lu, Yanhui;Wyckhuys, Kris A. G.;Desneux, Nicolas

    关键词：Agroecology; context dependency; ecological based pest management; ecological intensification; host quality

  • Epigenetics in the modern era of crop improvements

    作者：Xue, Yan;Deng, Xing Wang;Cao, Xiaofeng;Deng, Xian;Cao, Xiaofeng;Deng, Xian;Chen, Xiangsong;Yang, Hongchun;Ding, Yong;Dong, Aiwu;Liu, Bing;Ren, Guodong;Zhang, Yijing;Duan, Cheng-Guo;Fang, Xiaofeng;Qi, Yijun;Gong, Lei;Liu, Bao;Xu, Zheng-Yi;Gong, Zhizhong;Gong, Zhizhong;Gu, Xiaofeng;He, Chongsheng;He, Hang;He, Shengbo;He, Xin-Jian;He, Yan;Tian, Zhixi;He, Yuehui;Jia, Guifang;Wang, Yuan;Jiang, Danhua;Song, Xianwei;Jiang, Jianjun;Lai, Jinsheng;Lai, Jinsheng;Lai, Jinsheng;Lai, Jinsheng;Lai, Jinsheng;Lang, Zhaobo;Zhu, Jian-Kang;Li, Chenlong;Li, Qing;Li, Xingwang;Yan, Wenhao;Zhou, Dao-Xiu;Luo, Xiao;Qian, Weiqiang;Song, Qingxin;Wang, Jia-Wei;Xu, Lin;Wu, Liang;Wu, Zhe;Xia, Rui;Xiao, Jun;Zhao, Yusheng;Zhai, Jixian;Zhong, Xuehua;Zhou, Dao-Xiu;Zhou, Ming;Zhou, Yue;Zhu, Bo;Liu, Qikun

    关键词：epigenetics; plant development; plant immunity; crop improvement; stress responses

  • Single-cell transcriptome atlas of lamprey exploring Natterin- induced white adipose tissue browning

    作者：Pang, Yue;Du, Zeyu;Zhang, Jin;Lu, Jiali;Li, Jun;Dong, Xinrui;Zhao, Zhisheng;Chuan, Shunqin;Sun, Mingjie;Li, Qingwei;Pang, Yue;Du, Zeyu;Zhang, Jin;Lu, Jiali;Li, Jun;Dong, Xinrui;Zhao, Zhisheng;Chuan, Shunqin;Sun, Mingjie;Li, Qingwei;Qin, Yating;Liu, Qun;Han, Kai;Yuan, Zengbao;Pan, Shanshan;Xu, Mengyang;Wang, Dantong;Li, Zhen;Chen, Yadong;Song, Yue;Zhan, Liping;Cui, Wei;Wang, Jun;Fan, Guangyi;Qin, Yating;Liu, Qun;Han, Kai;Fan, Guangyi;Qin, Yating;Liu, Qun;Han, Kai;Song, Yue;Qin, Yating;Fan, Guangyi;Yuan, Zengbao;Xu, Mengyang;Wang, Dantong;Gu, Ying;Yang, Huanming;Xu, Xun;Liu, Xin;Fan, Guangyi;Xu, Mengyang;Fan, Guangyi;Li, Shuo;Zhang, Zhe;Ni, Ming;Jia, Xiaodong;Xia, Zhangyong;Yue, Zhen;Fan, Guangyi;Gu, Ying;Yang, Huanming;Xu, Xun;Liu, Xin

    关键词：

  • Cadmium Exposure Induces Inflammation Through Oxidative Stress-Mediated Activation of the NF-κB Signaling Pathway and Causes Heat Shock Response in a Piglet Testis

    作者：Li, Yulong;Wang, Hongbao;Wang, Yanfei;Li, Yulong

    关键词：Cadmium; Piglet testis; Oxidative stress; Inflammation; Heat shock response

  • The highly allo-autopolyploid modern sugarcane genome and very recent allopolyploidization in Saccharum

    作者：Zhang, Jisen;Hua, Xiuting;Wang, Baiyu;Yu, Zehuai;Gao, Ruiting;Wang, Tianyou;Zhang, Qing;Li, Zhen;Li, Yihan;Xu, Yi;Yao, Wei;Zhang, Muqing;Chen, Baoshan;Qi, Yiying;Wang, Yongjun;Wang, Yuhao;Li, Shuangyu;Qi, Nameng;Feng, Xiaoxi;Wu, Mingxing;Du, Cuicui;Deng, Zuhu;Qi, Yongwen;Huang, Yumin;Zhang, Yixing;Mei, Jing;Pan, Haoran;Liu, Jia;Chen, Shuqi;Fang, Yaxue;Ma, Panpan;Sun, Yuanchang;Ming, Ray;Tang, Haibao;Wang, Gang;Li, Qingyun;Feng, Xiaomin;Liu, Xinlong;Wang, Jianping

    关键词：

  • Effects of Chicken Manure Combinations on Compost Maturity and Microbial Community Dynamics in Industrial-Scale Composting

    作者：Wang, Weiwei;Zhang, Peng;He, Huiban;Liu, Hao;He, Haoxing;Cui, Zongjun;Yuan, Xufeng;Yuan, Xufeng;Wen, Boting;Yan, Jing

    关键词：Aerobic composting; Chicken manure; Compost maturity; Microbial community

  • Enhancing the synthesis efficiency of galacto-oligosaccharides of a β-galactosidase from Paenibacillus barengoltzii by engineering the active and distal sites

    作者：Yu, Haiyan;Wang, Yulu;Ying, Jiabao;Liu, Bolin;Mohamed, Abeer;Wei, Xue;Yang, Yuji;Xin, Fengjiao;Yang, Zhisen;Liu, Xin;Sun, Linfeng;Guan, Feifei;Miao, Miao;Jiang, Zhengqiang;Yang, Shaoqing;Wang, Yulu;Xin, Fengjiao

    关键词：beta-Galactosidase; GOS synthesis; Cryo-EM structure; Machine learning; Catalytic mechanism

微信小程序