Effects of Extraction Technique on the Content and Antioxidant Activity of Flavonoids from Gossypium Hirsutum linn. Flowers

文献类型： 外文期刊

第一作者： Dong, Jiaxing

作者： Dong, Jiaxing;Wang, Xiao;He, Qing;Zhang, Chenxu;Chu, Jun;Li, Qinglin;Dong, Jiaxing;He, Qing;Zhang, Chenxu;Chu, Jun;Li, Qinglin;Zhou, Kehai;Ge, Xiaoyang;Xu, Na;Xu, Na

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关键词： cotton flowers flavonoids; extraction process; response surface methodology; antioxidant activity

期刊名称：MOLECULES （ 影响因子：4.927； 五年影响因子：5.11 ）

ISSN：

年卷期： 2022 年 27 卷 17 期

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收录情况： SCI

摘要： Cotton is one of the Uyghur medical materials in China and is rich in flavonoids. Flavonoids have important pharmacological effects. The yield of flavonoids in traditional extraction methods is low, which affects the development of flavonoids. Therefore, it is urgent to optimize the extraction techniques. The yield of flavonoids in cotton flowers was effectively improved by response surface methodology, and the highest yield of flavonoids reached 5.66%, and the optimal extraction process conditions were obtained. The DPPH free radical scavenging rate, hydroxyl free radical scavenging rate, superoxide anion free radical scavenging rate, and reducing ability were tested to reflect the antioxidant capacity of flavonoids. The flavonoids had an excellent antioxidant effect. Cell experiments suggested that the flavonoids had the effect of protecting glutamate-induced damage to HT-22 cells. The results of this study provide a theoretical basis for the extraction of cotton flowers flavonoids and the comprehensive evaluation of antioxidant products, as well as the extraction of other plant flavonoids.

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