Sensitive Electrochemical Immunosensor for Procymidone Detection Based on a Supramolecular Amplification Strategy
文献类型: 外文期刊
第一作者: Ai, Qiushuang
作者: Ai, Qiushuang;Yu, Xiren;Dong, Yifan;Zhang, Li;Liang, Jingtian;Zhang, Dawen;Qiu, Suyan
作者机构:
期刊名称:ACS OMEGA ( 影响因子:4.3; 五年影响因子:4.4 )
ISSN: 2470-1343
年卷期: 2025 年 10 卷 3 期
页码:
收录情况: SCI
摘要: A sensitive electrochemical immunosensor for procymidone detection was developed based on a supramolecular amplification strategy. beta-Cyclodextrin (beta-CD)-based nanomaterials were employed to immobilize ferrocene derivative (FC)-functionalized antibodies/antigens through host-guest interactions. With the presence of procymidone, the formed beta-CD-labeled bioconjugates were immobilized on the antibody-modified electrode after the immunoreaction, indicating fabrication of the immunosensor. The FC/beta-CD complexes were with multiplex electroactive species and provided more sites for recognition groups, resulting in signal amplification of the sensor. Monitored with differential pulse voltammetry, the proposed immunosensor exhibited a wide linear range from 5 pM to 0.1 mu M with a low detection limit (LOD) of 1.67 pM. The as-prepared immunosensor possessed high sensitivity, specificity, and stability and showed great potential for monitoring procymidone in the field of food safety.
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