Influence of different dietary levels of zinc on performance, vitamin B-12, and blood parameters in lambs

文献类型： 外文期刊

第一作者： Wang, Runlian

作者： Wang, Runlian;Zhu, Xiaoping;Guo, Fucun;Zhang, Wei;Jia, Zhihai

作者机构：

关键词： cobalt;lamb;zinc;vitamin B-12;metabolites;rumen;blood

期刊名称：INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH （ 影响因子：1.784； 五年影响因子：1.835 ）

ISSN： 0300-9831

年卷期： 2006 年 76 卷 6 期

页码：

收录情况： SCI

摘要： This experiment was conducted to investigate the influence of different dietary levels of zinc (Zn) on performance, vitamin B-12 and blood parameters in lambs. Thirty six cannulated Poll Dorset x Small-tailed Han wether lambs were assigned randomly to four treatment groups: The control group, which was supplemented with 30 mg Co/kg dry matter (DM) to the basal diet; and the low-, medium- and high-Zn supplemented groups, supplementation of 50, 100, and 150 mg Zn/kg DM to the control diet, respectively. Lambs were housed in individual pens and the experiment lasted for 70 days. There was no significant difference in body weight gain and feed/gain between different treatment groups. The high-Zn supplemented lambs showed lower vitamin B-12 concentrations in both ruminal fluid and plasma, and higher methylmalonic acid and homocysteine concentrations in plasma compared with the control and low-Zn supplemented groups (p < 0.05). No significant difference was observed in these biochemical values between the control, the low-, and the medium-Zn supplemented groups (p > 0.05). Plasma folate concentration, glucose, and heme-dependent blood parameters were not influenced by dietary zinc level. It was concluded that the higher level of zinc supplementation had a negative effect on vitamin B-12 in lambs. Higher inclusion level of dietary zinc could inhibit vitamin B-12 synthesis in the rumen of lambs.

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