Understanding Mammalian Hair Follicle Ecosystems by Single-Cell RNA Sequencing

文献类型： 外文期刊

第一作者： Zheng, Qingbo

作者： Zheng, Qingbo;Zhang, Xiaolan;Bao, Pengjia;Zhou, Xuelan;Chu, Min;Guo, Xian;Liang, Chunnian;Yan, Ping;Zheng, Qingbo;Zhang, Xiaolan;Bao, Pengjia;Zhou, Xuelan;Chu, Min;Guo, Xian;Liang, Chunnian;Yan, Ping;Zheng, Qingbo;Pan, Heping

作者机构：

关键词： scRNA-seq; hair follicles; single cells

期刊名称：ANIMALS （ 影响因子：3.231； 五年影响因子：3.312 ）

ISSN： 2076-2615

年卷期： 2022 年 12 卷 18 期

页码：

收录情况： SCI

摘要： Single-cell sequencing technology can fully reflect the heterogeneity of cell populations at the single cell level, making it possible for us to re-recognize various tissues and organs. At present, the sequencing study of hair follicles is transiting from the traditional ordinary transcriptome level to the single cell level, which will provide diverse insights into the function of hair follicle cells. This review focuses on research advances in the hair follicle microenvironment obtained from scRNA-seq studies of major cell types in hair follicle development, with a special emphasis on the discovery of new subpopulations of hair follicles by single-cell techniques. We also discuss the problems and current solutions in scRNA-seq observation and look forward to its prospects.

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