Transcription and Post-translational Regulation of Autophagy in Insects

文献类型: 外文期刊

第一作者: Li, Rongsong

作者: Li, Rongsong;Tian, Ling;Li, Rongsong;Li, Kang;Tian, Ling;Li, Rongsong;Tian, Ling;Xiao, Yang;Li, Kang

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关键词: autophagy; transcription; post-translational modification; insect hormone; nutrient signal

期刊名称:FRONTIERS IN PHYSIOLOGY ( 影响因子:4.755; 五年影响因子:5.316 )

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年卷期: 2022 年 13 卷

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收录情况: SCI

摘要: Autophagy attracts great attention, and numerous progresses have been obtained in the last two decades. Autophagy is implicated in mammalian neurodegenerative diseases, tumorigenesis, as well as development in insects. The regulatory mechanism of autophagy is well documented in yeast and mammals, whereas it is not fully illustrated in insects. Drosophila melanogaster and Bombyx mori are the two well-studied insects for autophagy, and several insect-mammalian evolutionarily conserved or insect-specific mechanisms in regulating autophagy are reported. In this review, we summarize the most recent studies of autophagy regulated at both transcriptional and post-translational levels by insect hormone in cooperation with other signals, such as nutrient, which will provide a reference and deep thinking for studies on autophagy in insects.

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