Melatonin Modulates Lactation by Regulating Prolactin Secretion Via Tuberoinfundibular Dopaminergic Neurons in the Hypothalamus-Pituitary System
文献类型： 外文期刊
第一作者： Li, Hongyang
作者： Li, Hongyang;Wei, Jingya;Ma, Fengtao;Shan, Qiang;Gao, Duo;Jin, Yuhang;Sun, Peng
作者机构：
关键词： Melatonin; prolactin; dopamine; lactation; hypothalamus-pituitary system; tuberoinfundibular dopaminergic neurons
期刊名称：CURRENT PROTEIN & PEPTIDE SCIENCE （ 影响因子：3.272； 五年影响因子：3.183 ）
ISSN： 1389-2037
年卷期： 2020 年 21 卷 8 期
页码：
收录情况： SCI
摘要： In-depth studies have identified many hormones important for controlling mammary growth and maintaining lactation. One of these is melatonin, which is synthesized and secreted by the pineal gland to regulate circadian rhythms, improve antioxidant capacity, and enhance immunity. Prolactin is secreted by the pituitary gland and is associated with the growth and development of mammary glands as well as initiation and maintenance of lactation. The hypothalamus-pituitary system, the most important endocrine system in the body, regulates prolactin secretion mainly through dopamine released from tuberoinfundibular dopaminergic neurons. This review provides a reference for further study and describes the regulation of lactation and prolactin secretion by melatonin, primarily via the protection and stimulation of tuberoinfundibular dopaminergic neurons.
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