文献类型： 外文期刊
第一作者： Xie, Fei
作者： Xie, Fei;Liu, Zhengqun;Liu, Ming;Chen, Liang;Zhang, Hongfu;Ding, Wei
作者机构：
关键词： Glycolipid metabolism; amino acids (AAs); short chain fatty acids (SCFAs); intestinal microbial composition; metabolic pathways; metabolites
期刊名称：CURRENT PROTEIN & PEPTIDE SCIENCE （ 影响因子：3.272； 五年影响因子：3.183 ）
ISSN： 1389-2037
年卷期： 2020 年 21 卷 8 期
页码：
收录情况： SCI
摘要： Amino acids (AAs) and their metabolites regulate key metabolic pathways that are necessary for growth, reproduction, immunity and metabolism of the body. It has been convinced that metabolic diseases are closely related to disorders of glycolipid metabolism. A growing number of studies have shown that AAs are closely related to energy metabolism. This review focuses on the effects of amino acids (arginine, branched-chain amino acids, glutamine) and their metabolites (short chain fatty acids) on glycolipid metabolism by regulating PI3K/AKT/mTOR and AMPK signaling pathways and GPCRs receptors, reducing intestinal Firmicutes/Bacteroidetes ratio associated with obesity.
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