文献类型： 外文期刊
第一作者： Su, Mingjun
作者： Su, Mingjun;Chen, Raping;Qi, Shanshan;Sun, Dongbo;Shi, Da;Feng, Li
作者机构：
关键词： coronavirus; cell cycle arrest; cyclin-CDK complex; p53; nucleocapsid protein
期刊名称：FRONTIERS IN VETERINARY SCIENCE （ 影响因子：3.412； 五年影响因子：3.588 ）
ISSN：
年卷期： 2020 年 7 卷
页码：
收录情况： SCI
摘要： Coronaviruses are widespread in nature and infect humans, mammals and poultry. They cause harm to humans and animals. Virus-mediated cell cycle arrest is an essential strategy for viral survival and proliferation in the host cells. A clarification system of the mechanisms of virus-induced cell cycle arrest is highly desirable to promote the development of antiviral therapies. In this review, molecular mechanisms of coronavirus-induced cell cycle arrest were systematically summarized. Moreover, the common features of coronavirus-mediated cell cycle arrest were discussed. This review will provide a theoretical basis for further studies on the infection mechanisms and prevention of coronaviruses.
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