MoSec61 beta, the beta subunit of Sec61, is involved in fungal development and pathogenicity, plant immunity, and ER-phagy in Magnaporthe oryzae

文献类型： 外文期刊

第一作者： Wei, Yun-Yun

作者： Wei, Yun-Yun;Zhang, Yun-Ran;Lin, Fu-Cheng;Liu, Xiao-Hong;Liang, Shuang;Liang, Shuang;Lu, Jian-Ping;Lin, Fu-Cheng

作者机构：

关键词： Sec61β development; pathogenesis; plant immunity; ER-phagy

期刊名称：VIRULENCE （ 影响因子：5.882； 五年影响因子：6.489 ）

ISSN： 2150-5594

年卷期： 2020 年 11 卷 1 期

页码：

收录情况： SCI

摘要： The process of protein translocation into the endoplasmic reticulum (ER) is the initial and decisive step in the biosynthesis of all secretory proteins and many soluble organelle proteins. In this process, the Sec61 complex is the protein-conducting channel for transport. In this study, we identified and characterized the beta subunit of the Sec61 complex in Magnaporthe oryzae (MoSec61 beta). Compared with the wild-type strain Guy11, the Delta Mosec61 beta mutant exhibited highly branched mycelial morphology, reduced conidiation, high sensitivity to cell wall integrity stress, severely reduced virulence to rice and barley, and restricted biotrophic invasion. The turgor pressure of Delta Mosec61 beta was notably reduced, which affected the function of appressoria. Moreover, Delta Mosec61 beta was also sensitive to oxidative stress and exhibited a reduced ability to overcome plant immunity. Further examination demonstrated that MoSec61 beta affected the normal secretion of the apoplastic effectors Bas4 and Slp1. In addition, Delta Mosec61 beta upregulated the level of ER-phagy. In conclusion, our results demonstrate the importance of the roles played by MoSec61 beta in the fungal development and pathogenesis of M. oryzae.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序