Mussel-inspired synthesis of magnetic N-Halamine nanoparticles for antibacterial recycling

文献类型: 外文期刊

第一作者: Chai, Danxia

作者: Chai, Danxia;Hao, Xiufeng;Wang, Haixiao;Hao, Yujiao;Gao, Ge;Liu, Wenxin;Gao, Yue;Qu, Huihui;Dong, Alideertu;Wang, Heyuan;Wang, Lifang

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关键词: Magnetic nanoparticles; N-halamine coating; Dopamine; Mussel-inspired; Antibacterial use

期刊名称:COLLOID AND INTERFACE SCIENCE COMMUNICATIONS ( 影响因子:4.914; 五年影响因子:4.172 )

ISSN: 2215-0382

年卷期: 2020 年 39 卷

页码:

收录情况: SCI

摘要: Antibacterial N-halamine coatings are successful in avoiding and eliminating bacterial infections caused by bacterial contamination and biofilms on the surfaces. However, the N-halamine coatings remain a long-standing challenge faced by our healthcare system. Herein we reported a new mussel-inspired surface modification strategy to achieve N-halamine copolymer coatings with adhesive effects. The phenolic hydroxyl groups from Nhalamine copolymers are used for ligand exchange with oleic acid on the magnetic Fe3O4 nanoparticles for binding the N-halamine copolymer onto the surface of the nanoparticles. The as-synthesized N-halamine coatings endow the magnetic Fe3O4 nanoparticles antibacterial activity toward both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). Since the super-paramagnetism of Fe3O4 in core, the N-halamine coatings are separable magnetically and remain high inactivating efficiency toward bacteria even after five cycles. We believe that, with the advantage of mussel-inspired strategy, the N-halamine coatings should have great potential for use in antibacterial and biomedical fields.

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