Evidence for interspecies transmission route of pseudorabies virus via virally contaminated fomites

文献类型: 外文期刊

第一作者: Li, Hongxin

作者: Li, Hongxin;Pang, Yanling;Lin, Wencheng;Liang, Ruiying;Shi, Lijun;Cui, Shangjin

作者机构:

关键词: PRV; Bartha-K61; Transmission route; Pig; Dog

期刊名称:VETERINARY MICROBIOLOGY ( 影响因子:3.293; 五年影响因子:3.599 )

ISSN: 0378-1135

年卷期: 2020 年 251 卷

页码:

收录情况: SCI

摘要: Pseudorabies virus (PRV) is a zoonotic agent with a wide host range, causing significant economic losses in animal husbandry and potential public health risk globally. The causative agent has recently gained attention due to the inter-species transmission among different species of animals, even human beings. Although PRV's prevalence is found in many species of animals, regardless of whether the strain involved is a vaccine, classical or variant, few lines of evidence for the viral transmission route are available. Here, we reported that viral contamination is associated with the inter-species transmission of PRV. We found that PRV contamination was widely distributed in the environment of pig farms, that viral distribution in the environment is associated with the implementation of biosecurity measures, and that PRV could transmit from pigs to dogs through virally contaminated fomites. Collectively, our findings provide a basis for understanding the ecology and transmission route of PRV and underscore the importance of implementing biosecurity measures to control this disease.

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