Human gnathostomiasis: a neglected food-borne zoonosis

文献类型： 外文期刊

第一作者： Liu, Guo-Hua

作者： Liu, Guo-Hua;Fu, Yi-Tian;Liu, Guo-Hua;Sun, Miao-Miao;Elsheikha, Hany M.;Sugiyama, Hiromu;Ando, Katsuhiko;Sohn, Woon-Mok;Zhu, Xing-Quan;Yao, Chaoqun

作者机构：

关键词： Gnathostoma spp; Gnathostomiasis; Food-borne zoonosis

期刊名称：PARASITES & VECTORS （ 影响因子：3.876； 五年影响因子：3.959 ）

ISSN： 1756-3305

年卷期： 2020 年 13 卷 1 期

页码：

收录情况： SCI

摘要： BackgroundHuman gnathostomiasis is a food-borne zoonosis. Its etiological agents are the third-stage larvae of Gnathostoma spp. Human gnathostomiasis is often reported in developing countries, but it is also an emerging disease in developed countries in non-endemic areas. The recent surge in cases of human gnathostomiasis is mainly due to the increasing consumption of raw freshwater fish, amphibians, and reptiles.MethodsThis article reviews the literature on Gnathostoma spp. and the disease that these parasites cause in humans. We review the literature on the life cycle and pathogenesis of these parasites, the clinical features, epidemiology, diagnosis, treatment, control, and new molecular findings on human gnathostomiasis, and social-ecological factors related to the transmission of this disease.ConclusionsThe information presented provides an impetus for studying the parasite biology and host immunity. It is urgently needed to develop a quick and sensitive diagnosis and to develop an effective regimen for the management and control of human gnathostomiasis.

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