Clinical characteristics and follow-up analysis of 324 discharged COVID-19 patients in Shenzhen during the recovery period

文献类型： 外文期刊

第一作者： Liu, Han-Qing

作者： Liu, Han-Qing;An, Ya-Wen;Hu, Xiao-Peng;Zhao, Jia;Wang, Jian-Chun;Song, Shuo;Yuan, Bo;Chen, Kai-Jing;Hu, Qi;Wang, Cheng;Dong, Yu;Chen, Yong-Xin;Li, Wei-Xin;Sun, Chang-Qing

作者机构：

关键词： Covid-19; vaccine; epidemiology; antibody

期刊名称：INTERNATIONAL JOURNAL OF MEDICAL SCIENCES （ 影响因子：3.738； 五年影响因子：3.508 ）

ISSN： 1449-1907

年卷期： 2021 年 18 卷 2 期

页码：

收录情况： SCI

摘要： Objectives: Research on recovering COVID-19 patients could be helpful for containing the pandemic and developing vaccines, but we still do not know much about the clinical features, recovery process, and antibody reactions during the recovery period. Methods: We retrospectively analysed the epidemiological information, discharge summaries, and laboratory results of 324 patients. Results: In all, 15 (8.62%) patients experienced chest distress/breath shortness, where 8 of the 15 were severely ill. This means severely ill patients need an extended amount of time to recover after discharge; next, 20 (11.49%) patients experienced anxiety and 21 (12.07%) had headache/insomnia and a small fraction of them complained of anosmia/ageusia, indicating that these patients need treatment for mental and psychological health issues. Regarding the re-positive patients, their CT and laboratory test results showed no obvious evidence of illness progress or infectivity but a high anti-SARS-CoV-2 antibody expression. Conclusion: Recovered COVID-19 patients need psychological and physiological care and treatment, re-positivity can occur in any person, but juveniles, females, and patients with mild/moderate existing symptoms have higher rates of re-positivity, While there is no evidence that turning re-positive has an impact on their infectivity, but it still alerted us that we need differentiate them in the following managements.

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