文献类型： 外文期刊

第一作者： Duan, Xiao-Yan

作者： Duan, Xiao-Yan;Mei, Ren-Qiang;Duan, Xiao-Yan;Mei, Ren-Qiang;Duan, Xiao-Yan;Guo, Kun-Yuan;Zhang, Mei-De;Lv, Dong-Jin

作者机构：

关键词： Polyalthia simiarum; Triterpenes; Clerodane diterpenoids; Cytotoxic activities

期刊名称：FITOTERAPIA （ 影响因子：2.882； 五年影响因子：3.202 ）

ISSN： 0367-326X

年卷期： 2020 年 147 卷

页码：

收录情况： SCI

摘要： Two new C-31 triterpenes, polysimiaric acid A (1) and B (2) as well as one new clerodane diterpenoid, 16,16-dimethoxy-cleroda-3,13Z-dien-15-oic acid (3), together with six known compounds were isolated from Polyalthia simiarum. Their structures were determined by analysis of 1D and 2D NMR data. Three new compounds were tested for their cytotoxicity against five human tumour cell lines. Compound 3 showed cytotoxic activities against SMMC-7721 with the IC50 value of 22.43 mu M.

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