Effects of sugarcane vinegar supplementation on oxidative stress and weight reduction in hyperlipidaemic mice

文献类型： 外文期刊

第一作者： Li, Z. C.

作者： Li, Z. C.;Zheng, F. J.;Sun, J.;Lin, B.;Khoo, H. E.;Fang, X. C.;Li, Z. C.;Zheng, F. J.;Sun, J.;Chen, G. L.;Khoo, H. E.

作者机构：

关键词： antioxidant; lipid metabolism; health drink; hyperlipidaemia; metabolic complication

期刊名称：INTERNATIONAL FOOD RESEARCH JOURNAL （ 影响因子：1.014； 五年影响因子：1.333 ）

ISSN： 1985-4668

年卷期： 2020 年 27 卷 6 期

页码：

收录情况： SCI

摘要： The present work aimed to evaluate the efficacy of sugarcane vinegar supplementation in hyperlipidaemic mice. The mice were divided into six experimental groups: negative control, positive control (hyperlipidaemic), lovastatin, low-dose, medium-dose, and high-dose supplementation groups that received sugarcane vinegar via force-feeding. Body and organ weights of the mice were measured at the end of the study, and the collected blood was subjected to analysis of plasma lipid profile, plasma antioxidant enzymes, and other biochemical parameters for protection against oxidative stress. The results revealed that sugarcane vinegar supplementation significantly reduced body weight and improved plasma lipid profile of the mice. Although mice from the high-dose group showed a significant reduction in plasma triglyceride and plasma low-density lipoprotein-cholesterol, no changes in plasma total cholesterol and plasma high-density lipoprotein-cholesterol were observed. Supplementation of sugarcane vinegar in hyperlipidaemic mice neither reduced plasma glucose levels, inhibited plasma alpha-amylase activity, nor increased plasma lipase levels when compared with non-supplemented hyperlipidaemic mice. Oxidative stress was slightly improved in mice, in response to supplementation with sugarcane vinegar where all supplemented mice exhibited a significantly lower plasma malondialdehyde level, and the mice from the high-dose group exhibited a significantly higher plasma superoxide dismutase level when compared with the hyperlipidaemic group. As sugarcane vinegar reduced oxidative stress in mice, especially in mice supplemented with a high dosage of the vinegar, sugarcane vinegar could be a functional food with great potential for use in health-promoting beverages. (C) All Rights Reserved

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序