Genetic effects of MOGAT1 gene SNP in growth traits of Chinese cattle

文献类型： 外文期刊

第一作者： Lyu, Shijie

作者： Lyu, Shijie;Zhang, Zijing;Shi, Qiaoting;Chen, Fuying;Xu, Zhaoxue;Wang, Eryao;Yang, Peng;Liu, Yanyong;Song, Tian;Lei, Chuzhao;Chen, Hong;Huang, Yongzhen;Liu, Xian;Li, Zhiming;Ru, Baorui;Cai, Cuicui;Xie, Jianliang

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关键词： Single nucleotide polymorphism; MOGAT1 gene; Growth traits; Association analysis

期刊名称：GENE （ 影响因子：3.688； 五年影响因子：3.329 ）

ISSN： 0378-1119

年卷期： 2021 年 769 卷

页码：

收录情况： SCI

摘要： Single nucleotide polymorphism (SNP) has recently become one of the ideal genetic markers. SNP refers to the DNA sequence polymorphism caused by double nucleotide variation in the genome, including the conversion or transversion of segmented bases. The synthesis and metabolism of triglycerides are related to the changes of energy in the body of livestock, which in turn affects their growth and development. Studies have shown that MOGAT1 gene plays a role in the route of triglyceride synthesis. PCR-RFLP and agarose gel electrophoresis technology were used to type the SNP site of MOGAT1 gene at g.25940T > C in this study. Association analysis between typing results and growth trait data was detected by SPSS 20.0 software. Results show that MOGAT1 gene was in a low level of heterozygosity in Xianan, Qinchuan and Pinan cattle population (0 < PIC < 0.25), and in middle level of heterozygosity in YL cattle population(0.25 < PIC < 0.5). And genotype 'AA' was dominant gene in Chinese cattle population. In QC and XN cattle, genotype of GG possess advantage on Body weight (P < 0.05); in YL cattle, individuals with genotype of homozygous mutation decreased significantly on Chest depth (P < 0.05). The purpose of this research is to provide theoretical materials for molecular breeding of yellow cattle and to promote the process of improving the growth traits of Chinese local yellow cattle.

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