Cyclodextrin-derivatized hybrid nanocomposites as novel magnetic solid-phase extraction adsorbent for preconcentration of trace fluoroquinolones from water samples coupled with HPLC-MS/ MS determination

文献类型： 外文期刊

第一作者： Li, Fukai

作者： Li, Fukai;Wang, Min;Zhou, Jian;Yang, MengRui;Wang, TongTong;Li, Fukai;Wang, Min;Zhou, Jian;Yang, MengRui;Wang, TongTong

作者机构：

关键词： Fluoroquinolones; Magnetic solid-phase extraction; Cyclodextrin; HPLC-MS; MS; Adsorbent

期刊名称：MICROCHEMICAL JOURNAL （ 影响因子：3.594； 五年影响因子：3.273 ）

ISSN： 0026-265X

年卷期： 2021 年 164 卷

页码：

收录情况： SCI

摘要： A novel cyclodextrin-derivatized hybrid magnetic nanocomposite, denoted as Fe3O4@SiO2@CD, was fabricated and employed as the adsorbent of magnetic solid-phase extraction (MSPE) for preconcentration of elven fluoroquinolones (FQs) from water samples. The prepared nanoparticles exhibited excellent magnetic responsiveness (56.7 emu g-1), uniform size distribution (about 300 nm), good thermal and chemical stability, excellent reusability and superior chemical affinities to the target FQs via hydrogen bond, host?guest inclusion complexation and 7C?7C interactions. Under the optimized conditions, the MSPE was coupled with HPLC-MS/MS to sensitively quantify trance levels of FQs in environmental water. The developed method revealed satisfactory precision with RSDs lower than 4%, good linearity (R2 ? 0.9981), low limits of detection (0.0014?0.023 ?g L-1) and satisfactory recoveries (93.2?105%). Furthermore, the proposed approach was validated by analyzing the Certified Reference Material of GBW 10152 and GBW 10153 chicken meat powder. These results demonstrated that the Fe3O4@SiO2@CD nanoparticles are a promising magnetic adsorbent for FQs, and the established MSPEHPLC-MS/MS approach is suitable for simultaneous analysis of trace levels of FQs in actual samples.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序