Effect of Chronic Exposure to Pesticide Methomyl on Antioxidant Defense System in Testis of Tilapia (Oreochromis niloticus) and Its Recovery Pattern

文献类型： 外文期刊

第一作者： Meng, Shunlong

作者： Meng, Shunlong;Chen, Xi;Song, Chao;Fan, Limin;Qiu, Liping;Zheng, Yao;Chen, Jiazhang;Xu, Pao;Meng, Shunlong;Chen, Xi;Chen, Jiazhang;Xu, Pao

作者机构：

关键词： tilapia; biomarkers; catalase; glutathione peroxidase; glutathione reductase; glutathione-S-transferase; oxidized glutathione; reduced glutathione; superoxide dismutase

期刊名称：APPLIED SCIENCES-BASEL （ 影响因子：2.474； 五年影响因子：2.458 ）

ISSN：

年卷期： 2021 年 11 卷 8 期

页码：

收录情况： SCI

摘要： The chronic effect of environmental methomyl on the antioxidant system in testis of Nile tilapia (Oreochromis niloticus) and its recovery pattern was investigated. Tilapia were exposed to sublethal concentrations of 0.2, 2, 20 and 200 mu gL(-1) methomyl for 30 days and thereafter moved to methomyl-free water for 18 days. Antioxidant levels in testis, including glutathione peroxidase, catalase, glutathione-S-transferase, glutathione reductase, superoxide dismutase, reduced glutathione, oxidized glutathione were measured every 6 days during the period of exposure, and at 18 days after being transferred to methomyl-free water. The results showed that lower methomyl concentration (0.2 mu gL(-1)) had no effect on the above antioxidants, thus 0.2 mu gL(-1) could be seen as NOAEL for methomyl to tilapia. However, higher methomyl concentration of 2, 20 and 200 mu gL(-1) could significantly influence the above antioxidants. Glutathione peroxidase and oxidized glutathione increased significantly. On the contrary, reduced glutathione decreased significantly. Catalase, superoxide dismutase, glutathione reductase, glutathione-S-transferase increased at lower methomyl (2 and 20 mu gL(-1)), but decreased at higher methomyl (200 mu gL(-1)). The recovery test showed that oxidative damage caused by lower methomyl of 2 and 20 mu gL(-1) was reversible, and oxidative damage caused by higher methomyl of 200 mu gL(-1) was irreversible within 18 days of recovery period.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序