Comparative study of antimicrobial action of aloe vera and antibiotics against different bacterial isolates from skin infection

文献类型： 外文期刊

第一作者： Arbab, Safia

作者： Arbab, Safia;Wang Weiwei;Wei, Xiaojuan;Ahmad, Salah Uddin;Wu, Lingyu;Zhang, Jiyu;Arbab, Safia;Wang Weiwei;Wei, Xiaojuan;Ahmad, Salah Uddin;Wu, Lingyu;Zhang, Jiyu;Arbab, Safia;Wang Weiwei;Wei, Xiaojuan;Ahmad, Salah Uddin;Wu, Lingyu;Zhang, Jiyu;Ullah, Hanif

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关键词： Aloe vera; antibacterial; extract; skin infection; zone inhibition

期刊名称：VETERINARY MEDICINE AND SCIENCE （ 影响因子：0.954； ）

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收录情况： SCI

摘要： Background: We aimed to investigate the prevalence of Aloe Vera gel extract and antibiotic resistance against in Escherichia coli, Shigella, Salmonella spp and Staphylococcus aureus were isolated from animal's skin infection. Objective: The purpose of this study was has been designed to check the antibacterial effect of Aloe Vera against some common skin pathogens, and its comparison to commonly used antibiotics, with the aim to provide the cheap source of medication. Material and Methods: We performed a prospective study to determine 150 Skin infections were isolates obtained from septic wounds with sterile cotton swab at different Animal and applied to freshly prepared slants of nutrient agar, Mannitol Salt agar (Oxoid), and further conformation Catalase and a coagulase test were performed for biochemical characterization. We used Skin wound isolates were subjected to antibiotic resistance and Aloe Vera gel screening by disk diffusion method. Result: Four bacterial spp. strains were isolated from 150 skin infection of animals, the prevalence of organisms were found positive for Escherichia coli, Shigella, Salmonella Spp and Staphylococcus aureus respectively. Antibiotic resistance and susceptibility pattern of above isolates was also studies against 10 different clinically significant antibiotics. Aloe Vera leave gels were extracted with four different solvent were used during research. This result showed that ethanol extracts of Aloe Vera both leaf and root can be used alongside conventional antibiotics to fight agents of infections that are so prevalent in the skin infection. Conclusion: This investigation further assures that the plant extracts could be used for the treatment of microbial infections, our present findings we recommended that Aloe Vera gel at optimum concentration could be used as an antiseptic for prevention of some microbial skin wound infections. It is believed that this study could be used to identify new and more potent antimicrobial drugs of natural origin.

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