Comparative Proteomic Analysis of Different Parts of Taenia Hydatigena

文献类型： 外文期刊

第一作者： Cai, Mengting

作者： Cai, Mengting;Li, Yating;Ding, Juntao;He, Guitian;Guo, Xiaola;Zhang, Shaohua;Yan, Lujun;Zhang, Jing

作者机构：

关键词： Taenia hydatigena; scolex; cyst; cestode; proteome

期刊名称：FRONTIERS IN VETERINARY SCIENCE （ 影响因子：2.245； ）

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年卷期： 2021 年 8 卷

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收录情况： SCI

摘要： Taenia hydatigena, a globally distributed parasite, is a canine tapeworm and causes huge economic losses in the food industry. Using LC-MS/MS, the proteomes of T. hydatigena cyst scolex, designated as CS, and the cyst without the scolex, designated as CWS, were profiled and a total of 764 different proteins were identified, 664 of which were identified in CS, 412 identified in CWS, and 312 in both. Comparative analysis revealed that CS had more abundant proteins associated with growth and development, while CWS had more abundant proteins constituting a scaffolding and protective extracellular matrix. Consistent with the sequencing data, the abundance of the five selected proteins was validated to be higher in CWS than CS by Western blotting. The current data will provide a clue for further pinpointing a role of these proteins in the biology of T. hydatigena.

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