文献类型： 外文期刊
第一作者： Yan, Yunxiang
作者： Yan, Yunxiang;Li, Hong;Ma, Xiang;Tang, Yanqiong;Li, Juanjuan;Liu, Zhu;Yan, Yunxiang;Li, Hong;Ma, Xiang;Tang, Yanqiong;Li, Juanjuan;Liu, Zhu;Li, Ye;Yi, Kexian;Lin, Xiangmin
作者机构：
关键词： drug-resistant bacteria; zeolitic imidazolate framework; SmpB protein; biofilm; cell membrane
期刊名称：ACS INFECTIOUS DISEASES （ 影响因子：5.3； 五年影响因子：5.1 ）
ISSN： 2373-8227
年卷期： 2023 年
页码：
收录情况： SCI
摘要： The horizontal transfer of drug-resistant genes and the formation of biofilm barriers have threatened the therapeutic efficacy of conventional antibiotic drugs. Development of nonantibiotic agents with high delivery efficiency through bacterial biofilms is urgently required. A pyrithione (PT)-loading zeolitic imidazolate framework (ZIF-8@PT) is synthesized to destroy biofilms and improve the sensitivity of bacteria to PT. ZIF-8@PT can target and destroy the biofilm as well as the cell membrane, promoting the intracellular delivery of PT and possibly its interaction with SmpB, a protein that could regulate the drug resistance of bacteria. ZIF-8@PT effectively suppresses abdominal infections induced by multiresistant Aeromonas veronii C4 in rodent models without systemic toxicity. ZIF-8@PT promises wide applications in treating infections caused by multidrug-resistant bacteria through a dual mechanism of action.
分类号：
- 相关文献
作者其他论文 更多>>
-
Response of Interaction between Aboveground and Belowground Herbivorous to Corn Development
作者：Liu, Jinwen;Li, Hong;Zhang, Jinhua;Li, Jianping;Yan, Xiujuan
关键词：Aboveground herbivores; Belowground herbivores; Plant development; Community structure; Interactions
-
Contamination status, risk assessment, and control measures of heavy metals in tuber crops
作者：Liu, Yuqi;Zhang, Liuquan;Li, Ye;Xu, Minghao;Ji, Shengyang;Pan, Qiannan;Lu, Baiyi;Zhang, Jinzheng;Lu, Xiaojing;Li, Kaimian
关键词：Tuber crops; Heavy metals; Contamination status; Risk assessment; Cassava; Control measures
-
On-site rapid detection of multiple pesticide residues in tea leaves by lateral flow immunoassay
作者：Gao, Junxia;Zhang, Tianyi;Fang, Yihua;Zhao, Ying;Zhu, Guonian;Guo, Yirong;Yang, Mei;Zhao, Li;Li, Ye;Huang, Jun
关键词：Lateral flow immunoassay; Rapid detection; Pesticide multi -residue; Tea matrix; Sample rapid pretreatment
-
Parasite-derived microRNA let-7-5p detection for metacestodiasis based on rolling circular amplification-assisted CRISPR/Cas9
作者：Wang, Liqun;Pu, Guiting;Liu, Tingli;Chen, Guoliang;Li, Hong;Amuda, Tharheer Oluwashola;Cao, Shanling;Yan, Hongbin;Yin, Hong;Fu, Baoquan;Luo, Xuenong;Yin, Hong;Fu, Baoquan;Luo, Xuenong;Fu, Baoquan;Luo, Xuenong
关键词：diagnosis; let-7-5p; metacestodiasis; plasma; RCA-assisted CRISPR/Cas9
-
Interactive Effects of Selenium and Arsenic on their Accumulation, Translocation, Arsenic and Selenium Species, and Subcellular Distribution in Brassica Vegetables
作者：Qin, Yuyan;Wang, Yunru;Shi, Pengtao;Wu, Feng;Zhong, Yunjie;Li, Hong;Shan, Bin;Qin, Yuyan;Wang, Yunru;Shi, Pengtao;Wu, Feng;Li, Hong;Shan, Bin;Qin, Yuyan;Wang, Yunru;Shi, Pengtao;Wu, Feng;Zhong, Yunjie;Li, Hong;Shan, Bin
关键词：Arsenic; Selenium; Accumulation; Speciation; Subcellular distribution; Brassica vegetable
-
Development and Evaluation of a Loop-Mediated Isothermal Amplifcation (LAMP) Assay for Specific and Sensitive Detection of Puccinia melanocephala Causing Brown Rust in Sugarcane
作者：Wu, Weihuai;Wang, Guihua;Wang, Han;Zhu, Liqian;Liang, Yanqiong;Gbokie Jr, Thomas;Lu, Ying;Huang, Xing;He, Chunping;Yi, Kexian;Wang, Guihua;Gbokie Jr, Thomas;Qin, Jianfeng;Yi, Kexian
关键词：loop-mediated isothermal amplification (LAMP); internal transcribed spacer (ITS); sequence; molecular diagnosis; sugarcane brown rust (SCBR); SYBR Green I
-
Monitoring of parasite Orobanche cumana using Vis-NIR hyperspectral imaging combining with physio-biochemical parameters on host crop Helianthus annuus
作者：Li, Juanjuan;Farooq, Muhammad Ahsan;Huang, Qian;Zhou, Weijun;Pan, Tiantian;Liu, Fei;Xu, Ling;Najeeb, Ullah;Yun, Xiaopeng
关键词：Orobanche cumana; Sunflower; Vis-NIR hyperspectral imaging; Physio-biochemical parameters; Gene expression analysis
