Maillard Reaction Products with Anti-Tobacco Mosaic Virus Activities Generated in Processed Thermopsis lanceolata R. Br. Seed Extract

文献类型: 外文期刊

第一作者: Zhao, Li-Hua

作者: Zhao, Li-Hua;Hu, Zhan-Xing;Zhang, Peng;Zou, Ji-Bin;An, Qiao;Yi, Ping;Yuan, Chun-Mao;Yang, Jue;Gu, Wei;Huang, Lie-Jun;Hao, Xiao-Jiang;Hu, Zhan-Xing;Zou, Ji-Bin;An, Qiao;Yi, Ping;Yuan, Chun-Mao;Yang, Jue;Gu, Wei;Huang, Lie-Jun;Hao, Xiao-Jiang;Hao, Xiao-Jiang;Zhang, Peng;Hu, Zhan-Xing;Zou, Ji-Bin;An, Qiao;Yi, Ping;Yuan, Chun-Mao;Yang, Jue;Gu, Wei;Huang, Lie-Jun;Hao, Xiao-Jiang

作者机构:

期刊名称:JOURNAL OF ORGANIC CHEMISTRY ( 影响因子:4.198; 五年影响因子:4.031 )

ISSN: 0022-3263

年卷期: 2022 年 87 卷 17 期

页码:

收录情况: SCI

摘要: Six novel Maillard reaction products (MRPs) (1-6) were isolated from the processed Thermopsis lanceolata R. Br. seed extract, along with one biogenetically related intermediate (7). Compounds 1-4 possessed three rare dimerization patterns constructed by cytisine, whereas compounds 5 and 6 represented the first example of the addition products of cytisine and 5,6-dihydroxy-4-hexanolide. Their structures were elucidated by comprehensive spectroscopic data analysis and quantum chemistry calculations including GIAO C-13{H-1} NMR and ECD calculation, combined with single-crystal X-ray diffraction analysis. Biologically, compound 3 displayed significant anti-tobacco mosaic virus activity compared with the positive control ningnanmycin.

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