Strepolyketide D, a new SEK15-derived polyketide compound from salt-lake-derived Streptomyces sp. DBC5

文献类型: 外文期刊

第一作者: Bao, Xiao-Wei

作者: Bao, Xiao-Wei;Li, Yi-Xin;Liu, Xiao-Lu;Li, Yi-Xin;Zhang, Zhi-Dong;Xu, Li-Juan;Liu, Xiao-Lu;Song, Su-Qin;Chen, Xiao-Ming;Ma, Zhong-Jun;Xu, Li-Juan

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关键词: Streptomyces sp; polyketide; antioxidant activity; strepolyketide D

期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.61; 五年影响因子:1.591 )

ISSN: 1028-6020

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收录情况: SCI

摘要: A new SEK15-derived polyketide compound, strepolyketide D (1), was isolated from salt-lake-derived Streptomyces sp. DBC5, together with two known analogues (2-3). Their structures were elucidated based on spectroscopic analysis of IR, MS, 1 D and 2 D NMR. Compound 2 elicited moderate antioxidation with IC50 value of 39.26 mu g/ml. The results of the study revealed that salt-lake actinomycetes of Lake Dabancheng appear to have immense potential as a source of polyketide compounds.

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