A novel polymorphism of GDF5 gene and its association with body measurement traits in Bos taurus and Bos indicus breeds

文献类型： 外文期刊

第一作者： Liu, Yong Feng

作者： Liu, Yong Feng;Zan, Lin Sen;Zhao, Shuan Ping;Xin, Ya Ping;Lin, Qing;Tian, Wan Qiang;Li, Kui;Wang, Zhi Wei;Zan, Lin Sen

作者机构：

关键词： Cattle;GDF5 gene;SNP polymorphism;PCR-RFLP;Body measurement

期刊名称：MOLECULAR BIOLOGY REPORTS （ 影响因子：2.316； 五年影响因子：2.357 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Body measurement traits, influenced by genes and environmental factors, play numerous important roles in the value assessment of productivity and economy. Growth differentiate factor 5 (GDF5), involved in the development and maintenance of bone and cartilage, is an important candidate gene for body measurement traits selection through marker-assisted selection (MAS). In this study, based on the PCR-RFLP technology, we discovered and evaluated the potential association of the single nucleotide polymorphism (SNP) (T586C in exon 1) of the bovine GDF5 gene with body measurement traits in 985 Bos taurus breed, 42 Bos indicus breed and 76 Bos indicus x Bos taurus individuals. As the SNP marker, there were the significant effects on the Body length (BL) in the Bos taurus (BT) and Bos indicus x Bos taurus (BMY) populations (P < 0.05). In BT population, animals with the genotype TT had lower mean values for BL and Hip width (HW) than these with the TC and CC genotype (P < 0.01). In BMY population, animals with the genotype TC had lower mean values for BL than these with the genotype CC (P < 0.05). These results suggest that the SNP of the GDF5 gene could be a very useful genetic marker for body measurement traits in the bovine reproduction and breeding.

分类号： Q7

  • 相关文献

[1]Molecular cloning, expression and characterization of bovine UQCC and its association with body measurement traits. Liu, Yongfeng,Zan, Linsen,Zhao, Shuanping,Liu, Yongfeng,Huang, Honggang,Li, Yong,Tang, Zhonglin,Yang, Shulin,Li, Kui,Zan, Linsen. 2010

[2]Molecular characterization, polymorphism of bovine ZBTB38 gene and association with body measurement traits in native Chinese cattle breeds. Liu, Yongfeng,Zan, Linsen,Zhao, Shuanping,Xin, Yaping,Li, Linqiang,Liu, Yongfeng,Cui, Wentao,Tang, Zhonglin,Li, Kui,Zan, Linsen.

[3]Molecular cloning, characterization and association analysis of the promoter region of the bovine CDK6 gene. Liu, Y. F.,Zan, L. S.,Xin, Y. P.,Jiao, Y.,Cui, W. T.,Li, K.,Liu, Y. F.. 2011

[4]Molecular characterization, expression pattern, polymorphism and association analysis of bovine ADAMTSL3 gene. Liu, Yongfeng,Zan, Linsen,Zhao, Shuanping,Xin, Yaping,Jiao, Yang,Zhao, Shuanping,Li, Kui,Liu, Yongfeng.

[5]Association analysis of thyroglobulin gene variants with carcass and meat quality traits in beef cattle. Xu, Shang-Zhong,Gan, Qian-Fu,Hou, Guan-Yu,Xu, Shang-Zhong. 2008

[6]Morphological diversities and eco-geographical structuring of Ethiopian camel (Camelus dromedarius) populations. Yosef, T.,Kefelegn, K.,Mohammed, Y. K.,Mengistu, U.,Solomon, A.,Tadelle, D.,Han, J.. 2014

[7]Identification of BLAD and citrullinemia carriers in Chinese Holstein cattle. Li, Jianbin,Zhang, Yi,Zhang, Yuan,Li, Jianbin,Wang, Hongmei,Hou, Minghai,Zhong, Jifeng. 2011

[8]Genetic variability in Grapevine virus A from Vitis vinifera L. x Vitis labrusca L. in Sichuan, China. Xi, Dehui,Yuan, Shu,Lin, Honghui,Wang, Jianhui,Chen, Keling,Li, Hongwen,Liu, Xiao,Wang, Jianhui,Liu, Jianjun,Chen, Keling,Li, Hongwen,Liu, Xiao,Liu, Jianjun,Ercisli, Sezai. 2012

[9]The Polymorphism of a Mutation of IGF-1 Gene on Two Goat Breeds in China. Wang Mou,Yu Hui,Huang Yong-Zhen,Xin Jing-Jing,Xin Ya-Ping,Chen Hong,Liu Wu-Jun,Fang Yi,Huang Xi-Xia,Yao Xin-Kui,Yu Shi-Gang,Fang Guang-Xin,Tian Ke-Chuan,Chen Hong. 2010

[10]A PCR-RFLP Assay targeting RPS8 gene for the discrimination between bovine Babesia and Theileria species in China. Tian, Zhancheng,Du, Junzheng,Yang, Jifei,Liu, Aihong,Liu, Xiaocui,Liu, Guangyuan,Yin, Hong. 2015

[11]Genetic structure and low-genetic diversity suggesting the necessity for conservation of the Chinese Longsnout catfish, Leiocassis longirostris (Pisces : Bagriidae). Wang, ZW,Zhou, JF,Ye, YZ,Wei, QW,Wu, QJ. 2006

[12]Association of polymorphisms in the intron 1 of duck prolactin with egg performance. Li, Hui-Fang,Zhu, Wen-Qi,Chen, Kuan-Wei,Zhang, Tang-Jie,Song, Wei-Tao. 2009

[13]A Dominant Major Locus in Chromosome 9 of Rice (Oryza sativa L.) Confers Tolerance to 48 degrees C High Temperature at Seedling Stage. Wei, He,Liu, Jianping,Wang, Ya,Zhang, Xiaobo,Wang, Liangchao,Zhang, Jiwen,Tu, Jumin,Huang, Nongrong,Zhong, Xuhua. 2013

[14]A Mutation at Exon 3 of KIF-1 Gene of Three Goat Breeds in China. Tian Ke-Chuan,Liu Wu-Jun,Wang Qiong,Huang Xi-Xia,Yu Shi-Gang. 2011

[15]Characterization of a novel cry8 gene specific to Melolonthidae pests: Holotrichia oblita and Holotrichia parallela. Yan, Guixin,Zhang, Jie,Song, Fuping,Wang, Rongyan,Feng, Shuliang,Huang, Dafang.

[16]Identification of Self-Incompatibility Genotypes in Some Sand Pears (Pyrus pyrifolia Nakai) by PCR-RFLP Analysis. Gu Qing-qing,Zhang Qing-lin,Luo Zheng-rong,Gu Qing-qing,Hu Hong-jue,Chen Qi-liang. 2009

[17]Authentication of Panax ginseng from its Adulterants by PCR-RFLP and ARMS. Diao, Ying,Hu, Zhong-Li,Diao, Ying,Lin, Xian-Ming,Liao, Chao-Lin,Tang, Chun-Zi,Chen, Zhong-Jian. 2009

[18]Prevalence and genetic characterization of Toxoplasma gondii in badgers (Melogale moschata) in southern China by PCR-RFLP. Kai, Chen,Si-Yang, Huang,Jin-Lei, Wang,Qiu-Xia, Yao,Xing-Quan, Zhu,Si-Yang, Huang,Qiu-Xia, Yao,Xing-Quan, Zhu,Rong-Liang, Hu,Shou-Feng, Zhang,Quan, Liu.

[19]Analysis on DNA sequence of KiSS-1 gene and its association with litter size in goats. Cao, G. L.,Chu, M. X.,Fang, L.,Di, R.,Feng, T.,Li, N..

[20]An SNP in the MyoD1 gene intron 2 associated with growth and carcass traits in three duck populations. Wu, Y.,Pi, J. S.,Pan, A. L.,Pu, Y. J.,Du, J. P.,Shen, J.,Liang, Z. H.,Wu, Y.,Zhang, J. R..

作者其他论文 更多>>

微信小程序