A New Ergosterol-Type Steroid Isolated from the Nicotiana tabacum-Derived Endophytic Fungus Aspergillus sp. TE-65L
文献类型： 外文期刊
第一作者： Huang, Xin-Rong
作者： Huang, Xin-Rong;Si, Tong;Huang, Xin-Rong;Jiang, Chao-Nan;Zhang, Peng;Zhang, Zhong-Feng
作者机构：
关键词： Aspergillus sp.; endophytic fungus; secondary metabolite; steroid; antifungal activity
期刊名称：RECORDS OF NATURAL PRODUCTS （ 影响因子：1.9； 五年影响因子：1.8 ）
ISSN： 1307-6167
年卷期： 2023 年
页码：
收录情况： SCI
摘要： Chemical investigation on the fungal strain Aspergillus sp. TE-65L, which was previously isolated from cultivated tobacco (Nicotiana tabacum L.), led to the production of four steroids including a new ergosterol-type steroid, namely aspergosterol A (1). Their chemical structures were established by detailed spectroscopic analysis of 1D/2D NMR and HRESIMS data. Compound 1 was found to possess anti-phytopathogenic activities against Alternaria alternate, Botrytis cinerea, and Fusarium oxysporum, with MIC values of 4, 8, and 16 mu g/mL.
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