Transcriptome analysis and histopathology of the mud crab (Scylla paramamosain) after air exposure
文献类型： 外文期刊
第一作者： Cheng, Chang-Hong
作者： Cheng, Chang-Hong;Ma, Hong-Ling;Deng, Yi-Qin;Feng, Juan;Chen, Xiao-Long;Guo, Zhi-Xun
作者机构：
关键词： Scylla paramamosain; Air exposure; Transcriptomic analysis; Oxidative stress
期刊名称：COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY （ 影响因子：3.228； 五年影响因子：3.289 ）
ISSN： 1532-0456
年卷期： 2020 年 228 卷
页码：
收录情况： SCI
摘要： The mud crab, Scylla paramamosain, is an economically-important crab in China. Air exposure is an important environmental stressor during mud crab culture and transportation. Adaptive mechanisms responding to air exposure in mud crabs are still poorly understood. In this study, mud crabs were exposed to air for 120 h. Air exposure decreased total hemocyte counts, led to cytological damage, and caused high mortality. Transcriptomic analysis was conducted at 0, 6 and 96 h after air exposure. A total of 3530 differentially expressed genes (DEGs) were identified. DEGs were mainly involved in the oxidative stress response, metabolism, cellular processes, signal transduction, and immune functions. Transcriptomic analysis also revealed that genes of glycolysis and of the tricarboxylic acid cycle were key factors in regulating the mud crab adaptation to air exposure.
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