Review: The roles and functions of glutamine on intestinal health and performance of weaning pigs

文献类型： 外文期刊

第一作者： Ji, F. J.

作者： Ji, F. J.;Wang, L. X.;Yang, H. S.;Hu, A.;Yin, Y. L.;Ji, F. J.;Ji, F. J.;Wang, L. X.;Yang, H. S.;Yin, Y. L.;Ji, F. J.;Wang, L. X.;Yang, H. S.;Yin, Y. L.;Yin, Y. L.

作者机构：

关键词： swine; weaning stress; functional amino acid; barrier function; epithelial cell renewal

期刊名称：ANIMAL （ 影响因子：3.24； 五年影响因子：3.223 ）

ISSN： 1751-7311

年卷期： 2019 年 13 卷 11 期

页码：

收录情况： SCI

摘要： The gut is composed of a single layer of intestinal epithelial cells and plays important roles in the digestion and absorption of nutrients, immune and barrier functions and amino acid metabolism. Weaning stress impairs piglet intestinal epithelium structural and functional integrities, which results in reduced feed intake, growth rates and increased morbidity and mortality. Several measures are needed to maintain swine gut development and growth performance after weaning stress. A large body of evidence indicates that, in weaning piglets, glutamine, a functional amino acid, may improve growth performance and intestinal morphology, reduce oxidative damage, stimulate enterocyte proliferation, modulate cell survival and death and enhance intestinal paracellular permeability. This review focuses on the effects of glutamine on intestinal health in piglets. The aim is to provide evidentiary support for using glutamine as a feed additive to alleviate weaning stress.

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