RNA-SEQ STUDY OF HEPATIC RESPONSE OF YELLOW-FEATHER CHICKENS TO ACUTE HEAT STRESS

文献类型： 外文期刊

第一作者： Zhang, Quan

作者： Zhang, Quan;Luo, Yi Kang;Zhang, Bo Hai;Chan, Yan Zi;Huang, Lin Lin;Wang, Yin;Liang, Jia Ming;Zhang, Quan;Zhang, Xi Quan

作者机构：

关键词： yellow-feather chickens; liver; heat stress; RNA-seq

期刊名称：ANNALS OF ANIMAL SCIENCE （ 影响因子：2.09； 五年影响因子：2.103 ）

ISSN： 2300-8733

年卷期： 2020 年 20 卷 1 期

页码：

收录情况： SCI

摘要： The yellow-feather broiler is a popular poultry breed in Asia, particularly in China. In this study, we performed RNA-seq analysis to identify differentially expressed genes (DEGs) in the liver of yellow-feather broilers that had been subjected to acute heat stress treatment (38 +/- 1 degrees C for 4 h, recovery 2 h) and determine the response of the liver to high temperature and its effects on yellow-feather broiler physiology . We found that the cloaca! temperature and respiratory rate of yellow-feather chickens were significantly increased immediately after the initiation of acute heat stress (38 degrees C) treatment. And after recovery for 2 h, there was no difference in the cloaca! temperature and respiratory rate between the acute heat stress and control groups. A total of 834 DEGs were observed in response to heat stress by RNA-seq. Almost half of the DEGs were involved in the lipid and energy metabolism, including fatty acid metabolism (ACOX1, ACACA, ACSL1, AGSL6, ACAA1, ACAA2, HADHB, and FASN) and propunoate metabolism (ACSS2, ALDH2, ACACA, DLAT, ALDH7A1, MDH1, ME1, ABAT, SUCLG2, and ACSS3). Our findings provide the context for RNA-seq studies in the liver of yellow-feather chickens and suggest that the liver of yellow-feather broilers has the lipid and energy metabolism physiological mechanisms activated in response to heat stress.

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