The suppression effects of feeding and mechanisms in CRF system of animals

文献类型: 外文期刊

第一作者: Qi, Jinwen

作者: Qi, Jinwen;Zhou, Bo;Zhang, Xin;Li, Ya;Xu, Shaoqi;Wang, Mei;Chen, Hu;Tang, Ni;Wang, Shuyao;Wang, Bin;Chen, Defang;Li, Zhiqiong;Zhang, Xin

作者机构:

关键词: CRF; UCNs; CRF receptors; CRF-BP; Food intake; Feeding mechanisms

期刊名称:GENE ( 影响因子:3.688; 五年影响因子:3.329 )

ISSN: 0378-1119

年卷期: 2020 年 733 卷

页码:

收录情况: SCI

摘要: CRF system is comprised of 4 homologous lineages, 2 main receptors (CRF-R1 and CRF-R2), and a binding protein CRF-BP. The homologous lineages are corticotropin-releasing factor (CRF), urotensin I (UI)/sauvagine (SVG)/urocortin 1 (UCN1), urocortin 2 (UCN2), and urocortin 3 (UCN3), and UI, SVG, UCN1 are orthologous genes. CRF system genes are widely distributed in the brain and gastrointestinal tract, which may relate to feeding regulation. According the research progress about CRF system on mammals and non-mammals, this paper summarized the discovery, structure, tissue distribution, appetite regulation and mechanism of CRF system in animals, which can provide the reference for further research and production of feeding regulation and growth in mammals and fish species.

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