Recent advances in nucleic acid-based methods for detection of helminth infections and the perspective of biosensors for future development

文献类型： 外文期刊

第一作者： Ullah, Hanif

作者： Ullah, Hanif;Qadeer, Abdul;Cheng, Guofeng;Rashid, Muhammad;Rashid, Muhammad Imran

作者机构：

关键词： Biosensor; diagnosis; helminths; infection; nucleic acids

期刊名称：PARASITOLOGY （ 影响因子：3.234； 五年影响因子：3.118 ）

ISSN： 0031-1820

年卷期： 2020 年 147 卷 4 期

页码：

收录情况： SCI

摘要： Pathogenic helminth infections are responsible for severe health problems and economic losses worldwide. Timely and accurate diagnosis of helminth infections is critical for adopting suitable strategies for pathogen control. Here, we review recent advances in nucleic acid-based diagnostic methods, including polymerase chain reaction, quantitative qPCR, loop-mediated isothermal amplification and recombinase polymerase amplification, and discuss their advantages and disadvantages for diagnosing helminth infections. In addition, we highlight recent advances in biosensors for the detection of nucleic acid biomarkers that can potentially be used for the diagnosis of helminth infection.

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