Absorption, metabolism, and bioactivity of vitexin: recent advances in understanding the efficacy of an important nutraceutical

文献类型: 外文期刊

第一作者: Peng, Ye

作者: Peng, Ye;Gao, Ruichang;Sun, Quancai;Gan, Renyou;Li, Huabin;Yang, Mingxuan;McClements, David Julian

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关键词: flavonoid C-glycosides; food components; gut microbiota; protective effects; vitexin

期刊名称:CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION ( 影响因子:11.176; 五年影响因子:11.193 )

ISSN: 1040-8398

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收录情况: SCI

摘要: vitexin, an apigenin-8-C-glucoside, is widely present in numerous edible and medicinal plants. vitexin possesses a variety of bioactive properties, including antioxidation, anti-inflammation, anti-cancer, neuron-protection, and cardio-protection. Other beneficial health effects, such as fat reduction, glucose metabolism, and hepatoprotection, have also been reported in recent studies. This review briefly discusses the absorption and metabolism of vitexin, as well as its influence on gut microbiota. Recent advances in understanding the pharmacological and biological effects of vitexin are then reviewed. Improved knowledge of the absorption, metabolism, bioactivity, and molecular targets of vitexin is crucial for the better utilization of this emerging nutraceutical as a chemopreventive and chemotherapeutic agent.

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