Perspective on the development of synthetic microbial community (SynCom) biosensors

文献类型: 外文期刊

第一作者: Yuan, Jing

作者: Yuan, Jing;Trivedi, Pankaj;Yuan, Jing;Trivedi, Pankaj;Yuan, Jing;Ratti, Carlo;Zhao, Kankan;Tan, Xiangfeng;Xue, Ran;Zeng, Yuan;Zeng, Yuan

作者机构:

期刊名称:TRENDS IN BIOTECHNOLOGY ( 影响因子:17.3; 五年影响因子:18.1 )

ISSN: 0167-7799

年卷期: 2023 年 41 卷 10 期

页码:

收录情况: SCI

摘要: Synthetic microbial community (SynCom) biosensors are a promising technology for detecting and responding to environmental cues and target molecules. SynCom biosensors use engineered microorganisms to create a more complex and diverse sensing system, enabling them to respond to stimuli with enhanced sensitivity and accuracy. Here, we give a definition of SynCom biosensors, outline their construction workflow, and discuss current biosensing technology. We also highlight the challenges and future for developing and optimizing SynCom biosensors and the potential applications in agriculture and food management, biotherapeutic development, home sensing, urban and environmental monitoring, and the One Health foundation. We believe SynCom biosensors could be used in a real-time and remote-controlled manner to sense the chaos of constantly dynamic environments.

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