Lysine inhibition of expression of genes encoding type III secretion system in Ralstonia pseudosolanacearum and its virulence in host plants
文献类型： 外文期刊
第一作者： Han, Liangliang
作者： Han, Liangliang;Li, Runxiao;Huang, Jiajun;Guo, Tao;Zhang, Yong;Xiao, Xia;Ouyang, Ping;Liang, Tao;Hikichi, Yasufumi;Ohnishi, Kouhei
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期刊名称：JOURNAL OF GENERAL PLANT PATHOLOGY （ 影响因子：1.2； 五年影响因子：1.2 ）
ISSN： 1345-2630
年卷期： 2025 年 91 卷 5 期
页码：
收录情况： SCI
摘要： The type III secretion system (T3SS) is essential for Ralstonia pseudosolanacearum to infect host plants. Transcription of the T3SS genes was not activated in nutrient-rich casamino acid-peptone-glucose (CPG) broth, but activated in a minimal medium that might mimic metabolic signals of the host plant. CPG broth at 5% substantially impaired expression of T3SS genes. In tests of T3SS gene expression, l-lysine was found to be a novel inhibitor of expression of T3SS genes in non-acidic conditions and significantly impaired their expression via a PrhG-HrpB pathway and their motility and biofilm formation, which are also important for pathogenicity, and led to significant inhibition of symptom development in tomato plants.
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